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  • Reactions of 3-isochromanone with aromatic aldehydes--microwave assisted condensations performed on solid basic inorganic supports.

Reactions of 3-isochromanone with aromatic aldehydes--microwave assisted condensations performed on solid basic inorganic supports.

Journal of biochemical and biophysical methods (2006-05-09)
András Vass, András Földesi, Tamás Lóránd
초록

An improved Knoevenagel condensation of 3-isochromanone and aromatic aldehydes can be achieved by microwave irradiation on solid supports in the presence of various catalysts. This synthetic method offers some major advantages, especially the possibility to change the ratio of E/Z isomers.

MATERIALS
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Sigma-Aldrich
3-Isochromanone, 98%