콘텐츠로 건너뛰기
Merck
  • Aflatoxin B1: binding to DNA in vitro and alteration of RNA metabolism in vivo.

Aflatoxin B1: binding to DNA in vitro and alteration of RNA metabolism in vivo.

Science (New York, N.Y.) (1966-03-25)
M B Sporn, C W Dingman, H L Phelps, G N Wogan
초록

Aflatoxin B(1) binds to both native and denatured DNA, as shown by spectroscopy and equilibrium dialysis. It also strongly inhibits incorporation of cytidine into rat liver nuclear RNA and lowers the RNA content of the nucleus. The extremle toxicity and carcinogenicity of aflatoxin B(1) may be direct results of the affinity of this agent for DNA.

MATERIALS
제품 번호
브랜드
제품 설명

Supelco
Aflatoxin B1 solution, 2 μg/mL in acetonitrile, analytical standard