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Merck

Synthesis of Substituted Isatins.

Tetrahedron letters (2013-03-08)
Larry L Klein, Michael D Tufano
초록

Isatins are valuable intermediates for heterocyclic chemistry. Most of the common methods for their production are less than adequate when the number and lipophilicity of substituents on the targeted isatin are increased. Our group desired such molecules and identified an alternative method for their production.

MATERIALS
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Sigma-Aldrich
4-Tritylaniline, 97%