- Diaryl ether synthesis in supercritical carbon dioxide in batch and continuous flow modes.
Diaryl ether synthesis in supercritical carbon dioxide in batch and continuous flow modes.
Chemical communications (Cambridge, England) (2008-10-03)
Jin-Kyun Lee, Matthew J Fuchter, Rachel M Williamson, Gary A Leeke, Edward J Bush, Ian F McConvey, Simon Saubern, John H Ryan, Andrew B Holmes
PMID18830491
초록
A high yielding, batch mode synthesis of diaryl ethers and sulfides by an S(N)Ar fluoride-mediated process in scCO(2) has been developed; the use of a polymer-supported imidazolium fluoride reagent in batch mode led to the development of a fixed-bed continuous flow process, with high conversions.
MATERIALS