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Merck

Dolasetron-induced torsades de pointes.

Journal of clinical anesthesia (2007-12-18)
Sarah Turner, Letha Mathews, Pratik Pandharipande, Reid Thompson
초록

A 52-year-old woman with hypertension and Graves' disease was scheduled for surgical removal of a meningioma. Intraoperative events were significant for hypotension requiring a vasopressin infusion. Prophylactic dolasetron was administered to the patient before emergence. The patient's trachea was easily extubated and she was neurologically intact at the end of the surgical procedure. On transport to the neurological intensive care unit, the patient developed torsades de pointes, requiring cardiopulmonary resuscitation, before a return to normal sinus rhythm.

MATERIALS
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Sigma-Aldrich
Dolasetron mesylate hydrate, ≥98% (HPLC), powder