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  • [Methods for the protection against counterfeit medications. Part 2. The assessment of interlot dispersion of the metoprolol succinate tablets fabricated by different manufacturers].

[Methods for the protection against counterfeit medications. Part 2. The assessment of interlot dispersion of the metoprolol succinate tablets fabricated by different manufacturers].

Sudebno-meditsinskaia ekspertiza (2013-01-01)
V A Iakushev, M A Morozova, T E Elizarova, S B Fitilev, T V Pletneva
초록

This paper reports the results of analysis of the metoprolol succinate tablets fabricated by two different manufacturers, Akrikhin (Russia) and AstraZeneka (Sweden) by near-IR spectroscopy in the combination with the chemometric processing of the data obtained (discriminative analysis). It is concluded that this method is applicable for the assessment of interlot dispersion of the metoprolol succinate tablets.

MATERIALS
제품 번호
브랜드
제품 설명

Sigma-Aldrich
(±)-Metoprolol (+)-tartrate salt, ≥98% (titration), powder
Supelco
Metoprolol Tartrate, Pharmaceutical Secondary Standard; Certified Reference Material
Supelco
Metoprolol tartrate solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®
Metoprolol tartrate, European Pharmacopoeia (EP) Reference Standard