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Merck

Studying Kinetochore Kinases.

Methods in molecular biology (Clifton, N.J.) (2016-05-20)
Adrian T Saurin, Geert J P L Kops
초록

Mitotic kinetochores are signaling network hubs that regulate chromosome movements, attachment error-correction, and the spindle assembly checkpoint. Key switches in these networks are kinases and phosphatases that enable rapid responses to changing conditions. Describing the mechanisms and dynamics of their localized activation and deactivation is therefore instrumental for understanding the spatiotemporal control of chromosome segregation.

MATERIALS
제품 번호
브랜드
제품 설명

Sigma-Aldrich
Anti-phospho-Histone H3 (Ser10) Antibody, Mitosis Marker, Upstate®, from rabbit
Sigma-Aldrich
Anti-Mps1 Antibody, NT, clone 3-472-1, clone 3-472-1, Upstate®, from mouse