콘텐츠로 건너뛰기
Merck
  • Monoglycerides from the brown alga Sargassum sagamianum: Isolation, synthesis, and biological activity.

Monoglycerides from the brown alga Sargassum sagamianum: Isolation, synthesis, and biological activity.

Bioorganic & medicinal chemistry letters (2008-05-20)
Hyeun Wook Chang, Kyoung Hwa Jang, Doohyun Lee, Hee Ryong Kang, Tae-Yoon Kim, Bong Ho Lee, Byoung Wook Choi, Sanghee Kim, Jongheon Shin
초록

Polyunsaturated fatty acid-derived monoglycerides were characterized from the marine brown alga Sargassum sagamianum, collected from Jeju Island, Korea. A new compound of this structural class was isolated and determined to be 1-octadecatetraenoyl glycerol, by combined spectroscopic methods. Based on the structures and bioactivity of these compounds, a series of monoglycerides were synthesized using glycerol and various fatty acids. Several compounds exhibited moderate to significant inhibition of phospholipase A(2) and cyclooxygenase-2.

MATERIALS
제품 번호
브랜드
제품 설명

Sigma-Aldrich
1-Oleoyl-rac-glycerol, ≥99%
Sigma-Aldrich
1-Oleoyl-rac-glycerol, technical, ~40% (TLC)
Sigma-Aldrich
1-Stearoyl-rac-glycerol, ≥99%