Synthesis of indoleamine 2,3-dioxygenase inhibitory analogues of the sponge alkaloid exiguamine A.

Synthesis of indoleamine 2,3-dioxygenase inhibitory analogues of the sponge alkaloid exiguamine A.

Journal of medicinal chemistry (2008-04-09)

Gavin Carr, Marco K W Chung, A Grant Mauk, Raymond J Andersen

초록

Synthetic analogues of the sponge natural product exiguamine A (3) have been prepared and evaluated for their ability to inhibit indoleamine 2,3-dioxygenase in vitro.

MATERIALS

제품 번호

브랜드

제품 설명

219878

Sigma-Aldrich

4-Hydroxyindole, 99%

860646

Sigma-Aldrich

1-Methyl-DL-tryptophan, 97%