2-Propanol

2-Propanol in Analytical Chemistry

2-Propanol in HPLC 

Isopropanol is used to as a component of the mobile phase in HPLC separation. It can be combined with other solvents to achieve specific chromatographic conditions.

2-Propanol in Gas Chromatography 

Isopropanol is used to dissolve or dilute samples before injection into a gas chromatography system. It can also be utilized as a reagent in derivatization reactions prior to gas chromatography analysis.

2-Propanol in Preparative Chromatography

Preparative chromatography is a technique used for the separation and purification of larger quantities of compounds. Isopropanol is used as a component in the mobile phase composition, and for loading a sample onto the preparative chromatography column.

Gradient Grade 2-Propanol for Liquid Chromatography

Isopropanol is often used in gradient elution methods, where the composition of the mobile phase changes over time. By employing a gradient of isopropanol in combination with other solvents, it becomes possible to achieve effective separations of complex mixtures containing analyte with varying polarities.

2-Propanol as Reference Standard

Isopropanol is used as a pharmaceutical secondary standard in determining volatile solvents in herbal formulations by gas chromatography. The USP reference standard of 2-propanol is used in specified quality tests and assays. Also, isopropanol serves as a standard for analyzing tobacco.

Deuterated 2-Propanol

2-Propanol-d₈ is a deuterated derivative of isopropanol and is used in the preparation of 2-iodopropane-d₇. It also serves as a solvent for evaluating triplet decay constants, triplet lifetime, and photoreduction rate constants of benzophenone.

Isotopic/Labelled 2-Propanol

Labelled 2-Propanol (2-Propanol-1,3-¹³C₂) can be used in imaging techniques such as magnetic resonance spectroscopy (MRS) or positron emission tomography (PET) to investigate metabolic processes in vivo.

Anhydrous 2-Propanol

Anhydrous 2-Propanol can be used as a drying agent or desiccant, as well as a carrier or medium for delivering catalysts or reagents in synthetic reactions. It can also be used as a solvent in the synthesis of esters and ethers from alcohols and carboxylic acids.