SRP8027

CD24 (mouse): FC (human)

recombinant, expressed in HEK 293 cells, >90% (SDS-PAGE)

• 동의어(들): M1/69-J11D heat stable antigen, NaMN adenylyltransferase 1, Nectadrin, X62 Heat stable antigen (HSA)
• UNSPSC 코드: 12352200
• NACRES: NA.32

속성

• 생물학적 소스: mouse
• 재조합: expressed in HEK 293 cells
• 분석: >90% (SDS-PAGE)
• 형태: lyophilized
• 분자량: ~50 kDa by SDS-PAGE
• 포장: pkg of 50 μg
• 불순물: <0.06 EU/μg endotoxin, tested
• UniProt 수납 번호: P24807
• 배송 상태: wet ice
• 저장 온도: −20°C
• 유전자 정보: mouse ... CD24(100133941)

설명

일반 설명

CD24 is a highly glycosylated protein expressed as glycosyl-phosphatidyl-inositol (GPI) anchored molecule. Widely expressed, mainly on T cells, B cells and is upregulated in numerous types of cancers. It has costimulatory activity for antigen specific T cell responses. Polymorphisms of human CD24 are associated with several autoimmune diseases. Recently a new role as negative regulator of the immune response has been reported. CD24-deficient mice are more sensitive to inflammatory responses. CD24 together with the membrane protein SIGLEC interacts with danger-associated molecular patterns (DAMPs), such as HMGB1, HSP90 or HSP70. CD24/SIGLEC complex may differentially regulate the host response to DAMPs and PAMPs (pathogen-associated molecular patterns).

물리적 형태

Lyophilized from PBS.

재구성

Reconstitute with 50 μL deionized water.

기타 정보

Mouse CD24 (aa 27-52) is fused at the C-terminus to the Fc portion of human IgG1.

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable