SAB5700387

Anti-Phospho-p38 MAPK-T180/Y182 antibody produced in rabbit

• 동의어(들): CSBP, CSBP1, CSBP2, CSPB1, EXIP, MAPK14, Mxi2, PRKM14, PRKM15, RK, SAPK2A, p38, p38 MAPK, p38ALPHA
• UNSPSC 코드: 12352203
• NACRES: NA.43

속성

• 생물학적 소스: rabbit
• Quality Level: 100
• 항체 형태: affinity isolated antibody
• 항체 생산 유형: primary antibodies
• 클론: polyclonal
• 형태: buffered aqueous solution
• 분자량: 29; 34; 35; 41
• 종 반응성: mouse, human, rat
• 농도: 5.56 mg/ml
• 기술: immunofluorescence: 1:50-1:200; western blot: 1:500-1:2000
• UniProt 수납 번호: Q16539
• 배송 상태: wet ice
• 저장 온도: −20°C
• 타겟 번역 후 변형: phosphorylation (pThr180/pTyr182)
• 유전자 정보: human ... MAPK14(1432)

설명

일반 설명

The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

면역원

A synthetic phosphorylated peptide around T180 & Y182 of human p38 MAPK (NP_620581.1).

물리적 형태

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

저장 및 안정성

Store at -20℃. Avoid freeze / thaw cycles.

안전성 정보

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable