SAB4500756

Anti-APLF antibody produced in rabbit

affinity isolated antibody

• 동의어(들): APFL, C2orf13, Xip1, aprataxin and PNK-like factor
• UNSPSC 코드: 12352203
• NACRES: NA.41

속성

• 생물학적 소스: rabbit
• Quality Level: 100
• 결합: unconjugated
• 항체 형태: affinity isolated antibody
• 항체 생산 유형: primary antibodies
• 클론: polyclonal
• 형태: buffered aqueous solution
• 분자량: antigen 56 kDa
• 종 반응성: human, mouse
• 농도: ~1 mg/mL
• 기술: ELISA: 1:40000; immunohistochemistry: 1:50-1:100; western blot: 1:500-1:1000
• NCBI 수납 번호: Q8IW19
• UniProt 수납 번호: Q8IW19
• 배송 상태: wet ice
• 저장 온도: −20°C
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... APLF(200558)

설명

일반 설명

Aprataxin and PNKP-like factor (APLF) is also called as PALF and Xip1. It is located in the nucleus. APLF has a forkhead-associated (FHA) domain and two unique poly (ADP-ribose)-binding zinc finger (PBZ) domains in its C-terminal region. This gene is mapped to human chromosome 2p13.3.

면역원

The antiserum was produced against synthesized peptide derived from human APLF.

Immunogen Range: 82-131

생화학적/생리학적 작용

Aprataxin and PNKP-like factor (APLF) acts as a DNA repair factor. The forkhead-associated (FHA) domain of APLF helps to bind to the phosphorylated FHA domain binding motifs (FBMs) in XRCC1 and XRCC4. Other domains of APLF recruites APLF to sites of DNA damage.

특징 및 장점

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물리적 형태

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: nwg
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable