SAB4300028

Anti-phospho-MEF2A (pThr³¹²) antibody produced in rabbit

affinity isolated antibody

• 동의어(들): Anti-ADCAD1 antibody produced in rabbit, Anti-RSRFC4 antibody produced in rabbit, Anti-RSRFC9 antibody produced in rabbit, Anti-myocyte enhancer factor 2A antibody produced in rabbit
• UNSPSC 코드: 12352203
• NACRES: NA.41

속성

• 생물학적 소스: rabbit
• Quality Level: 100
• 결합: unconjugated
• 항체 형태: affinity isolated antibody
• 항체 생산 유형: primary antibodies
• 클론: polyclonal
• 형태: buffered aqueous solution
• 분자량: ~54 kDa
• 종 반응성: human, rat, mouse
• 농도: 1 mg/mL
• 기술: immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100; indirect immunofluorescence: 1:100-1:200
• 동형: IgG
• 면역원 서열: (L-A-TP-P-V)
• NCBI 수납 번호: NP_001124398.1
• UniProt 수납 번호: Q02078
• 배송 상태: wet ice
• 저장 온도: −20°C
• 타겟 번역 후 변형: phosphorylation (pThr312)
• 유전자 정보: human ... MEF2A(4205)

설명

면역원

Peptide sequence around phosphorylation site of threonine 312 (L-A-T(p)-P-V), according to the protein MEF2A.

특징 및 장점

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

표적 설명

The process of differentiation from mesodermal precursor cells to myoblasts has led to the discovery of a variety of tissue-specific factors that regulate muscle gene expression. The myogenic basic helix-loop-helix proteins, including myoD (MIM 159970), myogenin (MIM 159980), MYF5 (MIM 159990), and MRF4 (MIM 159991) are one class of identified factors. A second family of DNA binding regulatory proteins is the myocyte-specific enhancer factor-2 (MEF2) family. Each of these proteins binds to the MEF2 target DNA sequence present in the regulatory regions of many, if not all, muscle-specific genes. The MEF2 genes are members of the MADS gene family (named for the yeast mating type-specific transcription factor MCM1, the plant homeotic genes 'agamous' and 'deficiens' and the human serum response factor SRF (MIM 600589)), a family that also includes several homeotic genes and other transcription factors, all of which share a conserved DNA-binding domain.

물리적 형태

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable