종 반응성
rat
포장
kit of 96 wells (12 strips x 8 wells)
기술
ELISA: suitable
입력
sample type cell culture supernatant(s)
sample type serum
sample type plasma
assay range
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 10 pg/mL
standard curve range: 10.24-2500 pg/mL
검출 방법
colorimetric
배송 상태
wet ice
저장 온도
−20°C
유전자 정보
rat ... Mag(29409)
일반 설명
The antibody pair provided in this kit recognizes rat MAG / Myelin-associated Glycoprotein / Siglec-4a.
애플리케이션
For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
생화학적/생리학적 작용
Myelin-associated glycoprotein (MAG) is expressed in Schwann cells and oligodendrocytes. It inhibits the growth of axons. MAG also has a role in signal transduction pathways and cell adhesion. In complex with the neurite outgrowth inhibitor (Nogo) receptor, MAG acts on neurons via the p75 receptor. It activates and modulates the function of Ras homolog gene family, member A (RhoA).
신호어
Warning
유해 및 위험 성명서
예방조치 성명서
Hazard Classifications
Met. Corr. 1
Storage Class Code
8A - Combustible corrosive hazardous materials
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Myelin-associated glycoprotein inhibits the neuronal differentiation of neural progenitors.
Neuroreport, 20(7), 708-712 (2009)
Tissue sparing and functional recovery following experimental traumatic brain injury is provided by treatment with an anti-myelin-associated glycoprotein antibody.
The European Journal of Neuroscience, 24(11), 3063-3072 (2006)
Myelin-associated glycoprotein inhibits microtubule assembly by a Rho-kinase-dependent mechanism.
The Journal of Biological Chemistry, 281(23), 15970-15979 (2006)
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