N8159

Albumin, Nitrated from bovine serum

lyophilized powder

• 동의어(들): Nitrated BSA
• CAS Number: 9048-46-8
• MDL number: MFCD03454307
• UNSPSC 코드: 12352202
• NACRES: NA.41

속성

• 생물학적 소스: bovine
• Quality Level: 200
• 형태: lyophilized powder
• 기술: immunoblotting: suitable
• UniProt 수납 번호: P02769
• 배송 상태: wet ice
• 저장 온도: −20°C
• 유전자 정보: bovine ... ALB(280717)

설명

일반 설명

Albumin, Nitrated (Nitrated BSA), is prepared by chemical modification of bovine serum albumin (BSA) by peroxynitrite. Peroxynitrite (ONOO-), a potent oxidant is an important member of the family of reactive oxygen and nitrogen species.

애플리케이션

Positive control in immunoblotting assays for Anti-Nitrotyrosine (Sigma Product Number N 0409).

생화학적/생리학적 작용

Peroxynitrite promotes the nitration of tyrosine residues in proteins linked, oxidation of redox metal centers, DNA, lipids and nitrosation of cysteine residues in proteins, suggesting that peroxynitrite plays a major role in oxidative cellular damage. Peroxynitrite has been implicated in the pathogenesis of several inflammatory, infectious and degenerative human disease. These include neurological conditions such as Alzheimer′s disease, amyotrophic lateral sclerosis (ALS), the pathogenesis of asthma, atherosclerosis, and a variety of conditions precipitated by endothelial injury.

물리적 형태

Lyophilized from 0.01 M phosphate buffered saline, pH 7.4

제조 메모

Bovine serum albumin (BSA) nitrated with peroxynitrite.

분석 메모

Does not contain sodium azide

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable