M4199

Myelin Oligodendrocyte Glycoprotein (40-54), Rat, Mouse

lyophilized powder

• 동의어(들): MOG (40-54)
• 실험식(Hill 표기법): C₈₄H₁₂₇N₂₇O₂₁
• CAS Number: 507233-87-6
• Molecular Weight: 1851.08
• UNSPSC 코드: 12352202
• NACRES: NA.32

속성

• 생물학적 소스: rat
• Quality Level: 200
• 분석: ≥97% (HPLC)
• 형태: lyophilized powder
• 색상: white
• solubility: deionized water: soluble
• UniProt 수납 번호: Q61885; Q63345
• 저장 온도: −20°C
• 유전자 정보: mouse ... Mog(17441) ; rat ... Mog(24558)

설명

Amino Acid Sequence

Tyr-Arg-Ser-Pro-Phe-Ser-Arg-Val-Val-His-Leu-Tyr-Arg-Asn-Gly

생화학적/생리학적 작용

The 21-residue peptide MOG 35-55 contains an antigenic epitope responsible for the activation of CD8 encephalitogenic T cells in mice. Two truncated peptides, MOG 40-54 and MOG 44-54 were shown to bind the recombinant H-2Db protein. This complex then binds MOG specific CD8 T cells. While MOG 40-54 retained the full capability of inducing paralytic disease, MOG 44-54 only partialy causes clinical paralysis and central nervous system inflamation.

물리적 형태

Lyophilized from 0.1% aqueous TFA.

기타 정보

Lyophilized from 0.1% TFA in H2O

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable