C8395

Cephradine

≥90.0% (Cephradine, HPLC)

• 동의어(들): Cefradin
• 실험식(Hill 표기법): C₁₆H₁₉N₃O₄S
• CAS Number: 38821-53-3
• Molecular Weight: 349.40
• MDL number: MFCD00865048
• UNSPSC 코드: 51282517
• PubChem Substance ID: 24278342
• NACRES: NA.85

속성

• 분석: ≥90.0% (Cephradine, HPLC)
• 형태: powder
• solubility: ethanol: practically insoluble 96%; hexane: practically insoluble; water: slightly soluble
• 항생제 활성 스펙트럼: Gram-negative bacteria; Gram-positive bacteria
• 동작 모드: cell wall synthesis | interferes
• 저장 온도: 2-8°C
• SMILES string: [H][C@]12SCC(C)=C(N1C(=O)[C@H]2NC(=O)[C@H](N)C3=CCC=CC3)C(O)=O
• InChI: 1S/C16H19N3O4S/c1-8-7-24-15-11(14(21)19(15)12(8)16(22)23)18-13(20)10(17)9-5-3-2-4-6-9/h2-3,6,10-11,15H,4-5,7,17H2,1H3,(H,18,20)(H,22,23)/t10-,11-,15-/m1/s1
• InChI key: RDLPVSKMFDYCOR-UEKVPHQBSA-N

설명

일반 설명

Chemical structure: ß-lactam

애플리케이션

Cefradin was used to study the effect of expression, binding, and inhibition of PBP3 and other penicillin-binding proteins (PBPs) on bacterial cell wall mucopeptide synthesis.

생화학적/생리학적 작용

Cefradin is a semi-synthetic cephalosporin that inhibits the last stage of bacterial cell wall synthesis by binding to certain penicillin-binding proteins (PBPs), such as PBP3, which results in cell lysis. Cell lysis is mediated by bacterial cell wall autolytic enzymes. It is effective against Gram-positive and Gram-negative bacteria. Cefradin may also interfere with autolysin inhibitors.

기타 정보

Keep container tightly closed in a dry and well-ventilated place.

안전성 정보

• 픽토그램: GHS08,GHS07
• 신호어: Danger
• 유해 및 위험 성명서: H315,H317,H319,H334,H335
• 예방조치 성명서: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
• 표적 기관: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 2
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable