B7283

Benserazide hydrochloride

≥98% (HPLC), solid, L-aromatic amino acid decarboxylase inhibitor

• 동의어(들): DL-Serine 2-(2,3,4-trihydroxybenzyl)hydrazide hydrochloride
• 실험식(Hill 표기법): C₁₀H₁₅N₃O₅ · HCl
• CAS Number: 14919-77-8
• Molecular Weight: 293.70
• EC Number: 238-991-9
• MDL number: MFCD00078571
• UNSPSC 코드: 12352125
• PubChem Substance ID: 24277886
• NACRES: NA.77

속성

• product name: Benserazide hydrochloride, ≥98% (HPLC), solid
• 생물학적 소스: synthetic
• 분석: ≥98% (HPLC)
• 형태: solid
• solubility: H₂O: 10 mg/mL
• 주관자: Roche
• 저장 온도: room temp
• SMILES string: Cl.NC(CO)C(=O)NNCc1ccc(O)c(O)c1O
• InChI: 1S/C10H15N3O5.ClH/c11-6(4-14)10(18)13-12-3-5-1-2-7(15)9(17)8(5)16;/h1-2,6,12,14-17H,3-4,11H2,(H,13,18);1H
• InChI key: ULFCBIUXQQYDEI-UHFFFAOYSA-N
• 유전자 정보: human ... DDC(1644)

설명

일반 설명

Benserazide is a peripheral decarboxylase inhibitor.

애플리케이션

Benserazide has been used:

• to inhibit dopa-decarboxylase
• to induce dyskinesia
• to test on purified bacterial TDCs to assess the extent to which it could affect bacterial decarboxylases
• as a peripheral dopa decarboxylase inhibitor to treat mice

생화학적/생리학적 작용

Benserazide can block HK2 enzymatic activity in vitro. It is used along with levodopa to treat Parkinson′s disease.

Inhibitor of L-aromatic amino acid decarboxylase.

특징 및 장점

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound was developed by Roche. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

기타 정보

2024 CiteAb Award Winner for Supplier Succeeding in Parkinson′s Research

안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H315,H319,H335
• 예방조치 성명서: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• 표적 기관: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 2
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: dust mask type N95 (US), Eyeshields, Gloves