추천 제품
형태
liquid
Quality Level
농도
100 mg/mL in DMSO
색상
colorless to faint yellow
항생제 활성 스펙트럼
Gram-negative bacteria
Gram-positive bacteria
fungi
parasites
동작 모드
DNA synthesis | interferes
배송 상태
dry ice
저장 온도
−20°C
InChI
1S/C14H18N4O3.C10H11N3O3S/c1-19-10-5-8(6-11(20-2)12(10)21-3)4-9-7-17-14(16)18-13(9)15;1-7-6-10(12-16-7)13-17(14,15)9-4-2-8(11)3-5-9/h5-7H,4H2,1-3H3,(H4,15,16,17,18);2-6H,11H2,1H3,(H,12,13)
InChI key
WZRJTRPJURQBRM-UHFFFAOYSA-N
애플리케이션
Cotrimoxazole has been used as an antimicrobial agent.
생화학적/생리학적 작용
Cotrimoxazole, a combination of trimethoprim and sulfamethoxazole, interferes with the cellular metabolism of folic acid in the bacterial cell by blocking the biosynthesis of nucleotides. Trimethoprim binds to dihydrofolate reductase (DHFR) which inhibits the reduction of dihydrofolic acid (DHF) to tetrahydrofolic acid (THF), resulting in an antimicrobial effect. Sulfamethoxazole interferes with the synthesis of nucleic acids in sensitive microorganisms by blocking the conversion of p-aminobenzoic acid to the coenzyme dihydrofolic acid. The net effect of these actions is to inhibit thymidine synthesis which prevents bacterial DNA synthesis.
포장
1ml
제조 메모
prepared using a 1:5 mixture of trimethoprim:sulfamethoxazole
기타 정보
Keep container tightly closed in a dry and well-ventilated place.
신호어
Warning
유해 및 위험 성명서
Hazard Classifications
Aquatic Chronic 3 - Repr. 2
Storage Class Code
12 - Non Combustible Liquids
WGK
WGK 2
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
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H Abolhassani et al.
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Autoimmune disorders occur with a higher incidence in common variable immunodeficiency (CVID) patients than in the general population. To describe the clinical features of the autoimmune phenotype in patients with CVID. The hospital records of all diagnosed CVID patients referred
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In March 2012, a Salvadoran-American boy aged 7 years living in Maryland developed three slightly painful, well-demarcated, flat, gray-brown patches on his torso. A dermatologist in Washington, DC, suspected a fixed drug eruption (an erythema multiforme-like adverse drug reaction that
Diversity of Escherichia coli strains producing extended-spectrum beta-lactamases in Spain: second nationwide study.
Diaz MA, et al.
Journal of Clinical Microbiology, 48, 2840-2845 (2010)
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