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Merck
모든 사진(1)

문서

204M-1

Sigma-Aldrich

ALK Protein (ALK-1) Mouse Monoclonal Antibody

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About This Item

UNSPSC 코드:
12352203
NACRES:
NA.41

생물학적 소스

mouse

Quality Level

100
500

결합

unconjugated

항체 형태

culture supernatant

항체 생산 유형

primary antibodies

클론

ALK-1, monoclonal

설명

For In Vitro Diagnostic Use in Select Regions (See Chart)

형태

buffered aqueous solution

종 반응성

human

포장

vial of 0.1 mL concentrate (204M-14)
vial of 0.5 mL concentrate (204M-15)
bottle of 1.0 mL predilute (204M-17)
vial of 1.0 mL concentrate (204M-16)
bottle of 7.0 mL predilute (204M-18)

제조업체/상표

Cell Marque

기술

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100

동형

IgG3κ

제어

anaplastic large cell lymphoma

배송 상태

wet ice

저장 온도

2-8°C

시각화

cytoplasmic, nuclear

일반 설명

ALK-1 is a novel fusion protein which is detected in 60% of Anaplastic Large Cell Lymphomas and has proven to indicate improved prognosis in the ALK-1 (+) group.

품질


IVD

IVD

IVD

RUO

결합

ALK Protein Positive Control Slides, Product No. 204S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

물리적 형태

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

제조 메모

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

기타 정보

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

법적 정보

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

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문서 라이브러리 방문

B Falini et al.
The American journal of pathology, 153(3), 875-886 (1998-09-15)
The t(2;5)(p23;q35) translocation associated with CD30-positive anaplastic large cell lymphoma results in the production of a NPM-ALK chimeric protein, consisting of the N-terminal portion of the NPM protein joined to the entire cytoplasmic domain of the neural receptor tyrosine kinase
S Nakamura et al.
The American journal of surgical pathology, 21(12), 1420-1432 (1997-12-31)
The p80(NPM/ALK) expression activated by the t(2;5) (p23;q35) translocation recently has been shown to play an important role in the pathogenesis of anaplastic large cell lymphoma (ALCL). However, the clinicopathologic significance of identification of p80 among ALCL cases has not
K A Cataldo et al.
The American journal of surgical pathology, 23(11), 1386-1392 (1999-11-11)
Anaplastic large cell lymphoma (ALCL) is associated with the t(2;5)(p23;q35) translocation involving the anaplastic lymphoma kinase gene (ALK) and the nucleophosmin gene (NPM), which result in expression of a novel fusion protein, NPM-ALK (p80). Clinicopathologic studies have shown that ALK

자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..

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