135R-1

CD35 (EP197) Rabbit Monoclonal Primary Antibody

• 동의어(들): C3-binding protein, C3BR, C3b/C4b receptor, C4BR, CD35 antigen, CR1, Complement Receptor 1, Complement component (3b/4b) receptor 1 (Knops blood group), Knops blood group antigen
• UNSPSC 코드: 12352203

속성

• 생물학적 소스: rabbit
• Quality Level: 100; 500
• 결합: unconjugated
• 항체 형태: culture supernatant
• 항체 생산 유형: primary antibodies
• 클론: EP197, monoclonal
• 설명: For In Vitro Diagnostic Use in Select Regions (See Chart)
• 형태: buffered aqueous solution
• 종 반응성: human
• 포장: vial of 0.1 mL concentrate (135R-14); vial of 0.1 mL concentrate Research Use Only (135R-14-RUO); vial of 0.5 mL concentrate (135R-15); vial of 1.0 mL concentrate (135R-16); vial of 1.0 mL concentrate Research Use Only (135R-16-RUO); vial of 1.0 mL pre-dilute Research Use Only (135R-17-RUO); vial of 1.0 mL predilute ready-to-use (135R-17); vial of 7.0 mL pre-dilute ready-to-use Research Use Only (135R-18-RUO); vial of 7.0 mL predilute ready-to-use (135R-18)
• 제조업체/상표: Cell Marque^™
• 농도: 0.1-5.0 μg/mL (predilute); 2.5-125 μg/mL (concentrate)
• 기술: immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100 (concentrated)
• 동형: IgG
• 제어: tonsil
• 배송 상태: wet ice
• 저장 온도: 2-8°C
• 시각화: membranous
• 유전자 정보: human ... CR1(1378)

설명

일반 설명

CD35 (complement receptor 1) is a cell membrane-bound, monomeric glycoprotein found on numerous cell types including erythrocytes, leukocytes, glomerular podocytes, and follicular dendritic cells. The primary function of CD35 is to serve as the cellular receptor for C3b and C4b, the most important components of the complement system leading to clearance of foreign macromolecules. The Knops blood group system is a system of antigens located on this protein. The protein mediates cellular binding to particles and immune complexes that have activated complement. Follicular dendritic cells (FDC) are restricted to the B-cell regions of secondary lymphoid follicles. CD35 antigen is found on erythrocytes, B cells, a subset of T cells, monocytes, as well as eosinophils and neutrophils. Anti-CD35 is considered a mature B-cell marker which labels follicular dendritic reticulum cells and tumors derived from such cells such as follicular dendritic cell tumor/sarcoma.

품질

United States - IVD
Canada - IVD
European Union - IVD
Japan - RUO

결합

CD35 Positive Control Slides, Product No. 135S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

물리적 형태

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

제조 메모

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기타 정보

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

법적 정보

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

안전성 정보

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 2
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable