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Merck
모든 사진(1)

문서

ST1042

Sigma-Aldrich

Anti-PKD2 Rabbit pAb

liquid, Calbiochem®

동의어(들):

Anti-Protein Kinase D2

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About This Item

UNSPSC 코드:
12352203
NACRES:
NA.41

생물학적 소스

rabbit

Quality Level

항체 형태

affinity isolated antibody

항체 생산 유형

primary antibodies

클론

polyclonal

형태

liquid

포함

≤0.1% sodium azide as preservative

종 반응성

human

제조업체/상표

Calbiochem®

저장 조건

OK to freeze

동형

IgG

배송 상태

wet ice

저장 온도

2-8°C

타겟 번역 후 변형

unmodified

유전자 정보

human ... PKD2(5311)

일반 설명

Immunoaffinity purified rabbit polyclonal antibody. Recognizes the ~105 kDa PKD2 protein.
Recognizes the ~105 kDa PKD2 protein in HEK293 cells.
This Anti-PKD2 Rabbit pAb is validated for use in Immunoblotting, Immunoprecipitation for the detection of PKD2.

면역원

Human
a synthetic peptide corresponding to amino acids near the C-terminus of human PKD2

애플리케이션


Immunoblotting (1:500-1:5000)
Immunoprecipitation (1-4 g/mg lysate)

포장

Please refer to vial label for lot-specific concentration.

경고

Toxicity: Highly Toxic (H)

물리적 형태

In PBS.

재구성

Following initial use, aliquot and freeze (-20°C) for long-term storage. Avoid freeze/thaw.

분석 메모

Positive Control
HEK 293 cells

기타 정보

Rey, O., et al. 2003. Biochem. Biophys. Res. Commun.302, 817.
Sturany, S., et al. 2002. J. Biol. Chem.277, 29431.
Sturany, S., et al. 2001. J. Biol. Chem.276, 3310.
This antibody does not cross-react with PKD1 or PKD3. Antibody should be titrated for optimal use in individual systems.

법적 정보

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class Code

12 - Non Combustible Liquids

WGK

nwg

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


시험 성적서(COA)

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문서 라이브러리 방문

Jianfen Guo et al.
The Journal of biological chemistry, 286(8), 6500-6509 (2010-12-16)
Protein kinase D (PKD) exists as a family of structurally related enzymes that are activated through similar phosphorylation-dependent mechanisms involving protein kinase C (PKC). While individual PKD isoforms could in theory mediate distinct biological functions, previous studies identify a high
Clara Aicart-Ramos et al.
The Journal of biological chemistry, 291(45), 23516-23531 (2016-09-25)
Protein kinase D (PKD) isoforms are protein kinase C effectors in signaling pathways regulated by diacylglycerol. Important physiological processes (including secretion, immune responses, motility, and transcription) are placed under diacylglycerol control by the distinctive substrate specificity and subcellular distribution of
Tim Eiseler et al.
The Journal of biological chemistry, 291(1), 462-477 (2015-10-29)
Vesicle formation and fission are tightly regulated at the trans-Golgi network (TGN) during constitutive secretion. Two major protein families regulate these processes: members of the adenosyl-ribosylation factor family of small G-proteins (ARFs) and the protein kinase D (PKD) family of

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