생물학적 소스
rat
Quality Level
결합
unconjugated
항체 형태
purified antibody
항체 생산 유형
primary antibodies
클론
ER-TR7, monoclonal
정제법
using protein G
종 반응성
mouse, human
포장
antibody small pack of 100 μg
기술
immunofluorescence: suitable
immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable
동형
IgG2a
에피토프 서열
Unknown
UniProt 수납 번호
배송 상태
2-8°C
타겟 번역 후 변형
unmodified
일반 설명
Connective tissue is responsible for maintaining the form of the body and its organs and provides cohesion and internal support. It includes several types of fibrous tissue that vary only in their density and cellularity. The cells of connective tissue include fibroblasts and adipose cells that are relatively stationary and several types of motile migrating cells, such as mast cells, macrophages, monocytes, lymphocytes, plasma cells, and eosinophils. These cells of connective tissue develop during embryonic life from the mesenchyme. Fibroblasts are the least specialized cells in the connective-tissue family. They are dispersed in connective tissue throughout the body, where they secrete a nonrigid extracellular matrix that is rich in type I and/or type III collagen. In skin fibroblasts originate from two distinct lineage of cells: one lineage populates the papillary dermis, and the other lineage populates the reticular dermis, that have distinct cell markers and distinct functional abilities. Clone ER-TR specifically detects an antigen present in, and produced by, reticular fibroblasts. This clone is useful to stain the microanatomy of various organs, in particular the connective tissue framework in lymphoid organs. It is also shown to detect reticular fibroblasts in thymus. (Ref.: Van Vliet, E., et al. (1984). Eur. J. Immunol. 14(6); 524-529).
특이성
Clone ER-TR7 is a rat monoclonal antibody that detects Reticular fibroblasts.
면역원
Thymic stromal cells isolated from C3H mice.
애플리케이션
Quality Control Testing
Evaluated by Immunohistochemistry in Mouse thymus tissue sections.
Immunohistochemistry Applications: A 1:50 dilution of this antibody detected reticular fibroblasts in frozen section of Mouse thymus tissue.
Tested applications
Immunofluorescence Analysis: A representative lot detected Reticular fibroblasts clone ER-TR7 in Immunofluorescence applications (Van Vliet, E., et al. (1984). Eur J Immunol. 14(6):524-9; Nolte, M.A., et al. (2003). J Exp Med. 198(3):505-12; Sixt, M., et al. (2005). Immunity. 22(1):19-29; Link, A., et al. (2007). Nat Immunol. 8(11):1255-65; Odaka, C., et al. (2009). J Histochem Cytochem. 57(4):373-82; Schiavinato, A., et al. (2021). Eur J Immunol. 51(9):2345-2347).
Immunohistochemistry Applications: A representative lot detected Reticular fibroblasts clone ER-TR7 in Immunohistochemistry applications (Van Vliet, E., et al. (1984). Eur J Immunol. 14(6):524-9; Nolte, M.A., et al. (2003). J Exp Med. 198(3):505-12; Sixt, M., et al. (2005). Immunity. 22(1):19-29; Link, A., et al. (2007). Nat Immunol.;8(11):1255-65; Odaka, C., et al. (2009). J Histochem Cytochem. 57(4):373-82; Schiavinato, A., et al. (2021). Eur J Immunol. 51(9):2345-2347).
Note: Actual optimal working dilutions must be determined by end user as specimens, and experimental conditions may vary with the end user
Evaluated by Immunohistochemistry in Mouse thymus tissue sections.
Immunohistochemistry Applications: A 1:50 dilution of this antibody detected reticular fibroblasts in frozen section of Mouse thymus tissue.
Tested applications
Immunofluorescence Analysis: A representative lot detected Reticular fibroblasts clone ER-TR7 in Immunofluorescence applications (Van Vliet, E., et al. (1984). Eur J Immunol. 14(6):524-9; Nolte, M.A., et al. (2003). J Exp Med. 198(3):505-12; Sixt, M., et al. (2005). Immunity. 22(1):19-29; Link, A., et al. (2007). Nat Immunol. 8(11):1255-65; Odaka, C., et al. (2009). J Histochem Cytochem. 57(4):373-82; Schiavinato, A., et al. (2021). Eur J Immunol. 51(9):2345-2347).
Immunohistochemistry Applications: A representative lot detected Reticular fibroblasts clone ER-TR7 in Immunohistochemistry applications (Van Vliet, E., et al. (1984). Eur J Immunol. 14(6):524-9; Nolte, M.A., et al. (2003). J Exp Med. 198(3):505-12; Sixt, M., et al. (2005). Immunity. 22(1):19-29; Link, A., et al. (2007). Nat Immunol.;8(11):1255-65; Odaka, C., et al. (2009). J Histochem Cytochem. 57(4):373-82; Schiavinato, A., et al. (2021). Eur J Immunol. 51(9):2345-2347).
Note: Actual optimal working dilutions must be determined by end user as specimens, and experimental conditions may vary with the end user
Anti-Reticular fibroblasts, clone ER-TR7, Cat. No. MABF2804, is a rat monoclonal antibody that detects Reticular fibroblasts and is tested for use in Immunofluorescence and Immunohistochemistry.
물리적 형태
Purified rat monoclonal antibody IgG2a in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
저장 및 안정성
Recommended storage: +2°C to +8°C.
기타 정보
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
12 - Non Combustible Liquids
WGK
WGK 1
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
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