추천 제품
생물학적 소스
mouse
Quality Level
결합
ALEXA FLUOR™ 647
항체 형태
purified immunoglobulin
항체 생산 유형
primary antibodies
클론
A2B5-105, monoclonal
종 반응성(상동성에 의해 예측)
mammals
기술
flow cytometry: suitable
immunocytochemistry: suitable
동형
IgM
배송 상태
ambient
타겟 번역 후 변형
unmodified
일반 설명
A2B5 (also known as F12A2B5) is a cell surface ganglioside expressed on developing thymic epithelial cells, oligodendrocyte progenitors, and neuroendocrine cells. It is highly expressed in embryonic and neonatal tissue, but in the adult mammalian brain its expression is restricted mainly to areas that retain neurogenic potential, such as the subventricular zone (SVZ). Hence, A2B5 is considered as a marker for immature glial-committed precursors, which are permanently generated in the SVZ. Its expression is also considered as a marker for various cancers, including astrocytoma, glioma, pancreatic islet tumors, and squamous cell carcinoma. Explants from A2B5+ tumor cells display a typical progenitor morphology and clearly indicate their immature state. Tumors expressing A2B5 antigen exhibit higher rates of recurrence.
특이성
This monoclonal antibody detects A2B5 in mammalian cells.
면역원
Embryonic chicken retinal cells.
애플리케이션
Anti-A2B5 Antibody, clone A2B5-105, Alexa Fluor™ 647 Conjugate Cat. No. MAB312-AF647, is a highly specific mouse monoclonal antibody that targets A2B5 and has been tested in Immunocytochemistry and Flow Cytometry.
Flow Cytometry Analysis: 1:400 dilution from a representative lot immunostained the surface of PC12 cells.
The unconjugated antibody (Cat. No. MAB312) is also available for flow cytometry, immunocytochemistry, immunofluorescence, and immunohistochemistry applications.
The unconjugated antibody (Cat. No. MAB312) is also available for flow cytometry, immunocytochemistry, immunofluorescence, and immunohistochemistry applications.
품질
Evaluated by immunocytochemistry of PC12 cells.
Immunocytochemistry Analysis: A 1:100 Dilution of this antibody immunostained the surface of PC12 cells.
Immunocytochemistry Analysis: A 1:100 Dilution of this antibody immunostained the surface of PC12 cells.
물리적 형태
Purified mouse IgM Alexa Fluor™ 647 conjugate in PBS with 1.5% BSA and 0.05% sodium azide.
기타 정보
Concentration: Please refer to lot specific datasheet.
법적 정보
ALEXA FLUOR is a trademark of Life Technologies
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Storage Class Code
12 - Non Combustible Liquids
WGK
WGK 2
시험 성적서(COA)
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