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Merck
모든 사진(1)

Key Documents

AB9908

Sigma-Aldrich

Anti-QKI-7 Antibody

serum, Chemicon®

동의어(들):

Quaking Protein

로그인조직 및 계약 가격 보기


About This Item

UNSPSC 코드:
12352203
eCl@ss:
32160702
NACRES:
NA.41

생물학적 소스

rabbit

Quality Level

항체 형태

serum

항체 생산 유형

primary antibodies

클론

polyclonal

종 반응성

mouse, rat, human

제조업체/상표

Chemicon®

기술

immunoprecipitation (IP): suitable
western blot: suitable

UniProt 수납 번호

배송 상태

wet ice

타겟 번역 후 변형

unmodified

유전자 정보

human ... QKI(9444)

일반 설명

QKI is an RNA-binding protein that plays a central role in myelinization. Acts by regulating pre-mRNA splicing, mRNA export, mRNA stability and protein translation. It is regulated by alternative splicing.

특이성

QKI-7 (Quaking Protein). The antibody recognizes the ~42 kDa protein.

면역원

Synthetic peptide from mouse QKI-7.

애플리케이션

Anti-QKI-7 Antibody is an antibody against QKI-7 for use in IP & WB.
Research Category
Neuroscience
Research Sub Category
Developmental Neuroscience

RNA Binding Protein (RBP)

물리적 형태

Liquid.
Serum

저장 및 안정성

Maintain at -20&deg:C in undiluted aliquots for up to 12 months after date of receipt. Avoid repeated freeze/thaw cycles.

분석 메모

Control
Positive Control: Glial cells, astrocytes and oligodendrocytes.

법적 정보

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


시험 성적서(COA)

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문서 라이브러리 방문

Daniel Larocque et al.
Nature neuroscience, 8(1), 27-33 (2004-11-30)
The quaking (Qk) locus expresses a family of RNA binding proteins, and the expression of several alternatively spliced isoforms coincides with the development of oligodendrocytes and the onset of myelination. Quaking viable (Qk(v)) mice harboring an autosomal recessive mutation in
Zhejia Zhang et al.
Oncology letters, 15(4), 5841-5848 (2018-03-21)
Thyroid cancer is the most frequently occurring type of endocrine tumor, with a rapidly increasing incidence rate. MicroRNA (miR)-574-5p is a candidate oncogene in various types of cancer. The present study identified that miR-574-5p affected the cell cycle distribution and
Xinyun Chen et al.
Nature communications, 12(1), 89-89 (2021-01-06)
The RNA-binding protein QKI belongs to the hnRNP K-homology domain protein family, a well-known regulator of pre-mRNA alternative splicing and is associated with several neurodevelopmental disorders. Qki is found highly expressed in developing and adult hearts. By employing the human

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