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Merck
모든 사진(1)

Key Documents

AB5779

Sigma-Aldrich

Anti-Striatin Antibody

serum, Chemicon®

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About This Item

UNSPSC 코드:
12352203
eCl@ss:
32160702
NACRES:
NA.41

생물학적 소스

rabbit

Quality Level

항체 형태

serum

항체 생산 유형

primary antibodies

클론

polyclonal

종 반응성

mouse, human, rat

제조업체/상표

Chemicon®

기술

immunocytochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable

NCBI 수납 번호

UniProt 수납 번호

배송 상태

dry ice

타겟 번역 후 변형

unmodified

유전자 정보

human ... STRN(6801)

일반 설명

Striatin is found in all mammalian cells and may be involved in vesicular transport, dendrite growth and cellular signalling. It binds Protein phosphatase 2A (PP2A) A and C subunits and calmodulin and appears to modulate PP2A activity. It also binds the human homolog of the yeast protein, Mob1, which has been implicated in mitotic progression in yeast. It is a member of a family of proteins that also include SG2NA (striatin 3) and Zinedin (striatin 4).

특이성

Reacts with Striatin. No cross reactivity with SG2NA.

면역원

Synthetic Striatin peptide.

애플리케이션

Anti-Striatin Antibody detects level of Striatin & has been published & validated for use in IP, WB & IC.
Research Category
Neuroscience
Research Sub Category
Synapse & Synaptic Biology
Western blot: 1:500-1:1,000. The antibody reacts with the ~110 kDa striatin protein in 293 cell lysate.

Immunocytochemistry: 1:500

Immunoprecitation: 3 μL recommended as starting point.

Optimal working dilutions must be determined by the end user.

물리적 형태

Rabbit serum. Liquid containing 40% glycerol and 0.02% sodium azide.

저장 및 안정성

Maintain at -20°C in undiluted for up to 12 months after date of receipt. For long-term storage, may be stored at -80°C. Avoid repeated freeze/thaw cycles at temperatures below -20°C.

법적 정보

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


시험 성적서(COA)

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문서 라이브러리 방문

Vincent Ricchiuti et al.
The Journal of endocrinology, 211(1), 47-54 (2011-07-13)
Liberal or high-sodium (HS) intake, in conjunction with an activated renin-angiotensin-aldosterone system, increases cardiovascular (CV) damage. We tested the hypothesis that sodium intake regulates the type 1 angiotensin II receptor (AT(1)R), mineralocorticoid receptor (MR), and associated signaling pathways in heart
X X Yu et al.
Molecular biology of the cell, 12(1), 185-199 (2001-02-13)
Binding of different regulatory subunits and methylation of the catalytic (C) subunit carboxy-terminal leucine 309 are two important mechanisms by which protein phosphatase 2A (PP2A) can be regulated. In this study, both genetic and biochemical approaches were used to investigate
C S Moreno et al.
The Journal of biological chemistry, 275(8), 5257-5263 (2000-02-22)
Protein phosphatase 2A (PP2A) is a multifunctional serine/threonine phosphatase that is critical to many cellular processes including development, neuronal signaling, cell cycle regulation, and viral transformation. PP2A has been implicated in Ca(2+)-dependent signaling pathways, but how PP2A is targeted to
Sean E Thatcher et al.
Biology of sex differences, 6, 12-12 (2015-07-02)
Abdominal aortic aneurysms (AAAs) occur predominately in males. However, AAAs in females have rapid growth rates and rupture at smaller sizes. Mechanisms contributing to AAA progression in females are undefined. We defined effects of ovariectomy, with and without 17-β estradiol

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