219404

Cathepsin H, Human Liver

Cathepsin H, Human Liver, CAS 60748-73-4, is native cathepsin H from human liver that functions both as an aminopeptidase and as an endopeptidase.

• 동의어(들): Cathepsin H, Human Liver, CTSH, cat H, procathepsin h
• CAS Number: 60748-73-4
• 효소 위원회 번호: 3.4.22.16 (BRENDA, IUBMB)
• UNSPSC 코드: 12352202

속성

• Quality Level: 100
• 형태: liquid
• 특이 활성도: ≥200 mU/mg protein
• 제조업체/상표: Calbiochem^®
• 저장 조건: OK to freeze; avoid repeated freeze/thaw cycles
• 기술: activity assay: suitable
• 색상: colorless
• pH: 4.5
• solubility: soluble; water: soluble
• 적합성: suitable for Western blot
• NCBI 수납 번호: NM_004390
• UniProt 수납 번호: P09668
• 배송 상태: wet ice
• 저장 온도: −70°C
• 유전자 정보: human ... CTSH(1512)

설명

일반 설명

Research area: Cell signaling

Native Cathepsin H, from the human liver, is the only cathepsin with mono-aminopeptidase activity.

애플리케이션

Cathepsin H has been used to determine the potential of aziridinyl peptides to act as inhibitors of this protein and potentially explore their therapeutic applications.

생화학적/생리학적 작용

Cathepsin H, derived from human liver, serves dual functions as both an aminopeptidase and an endopeptidase. It plays a significant role in the catabolism of proteins within lysosomes. Cathepsin H is classified as an endoaminopeptidase because it can hydrolyze proteins, N-terminal substituted proteins, amino acid derivatives, and peptides with different chain lengths and N-terminal free amino acid derivatives. This protein is also observed to exhibit amidase and esterase activity.

포장

Please refer to vial label for lot-specific concentration.

경고

Toxicity: Standard Handling (A)

단위 정의

One unit is defined as the amount of enzyme that will hydrolyze 1.0 µmol H-Arg-βNA per min at 40°C, pH 6.8.

물리적 형태

In 100 mM NaCl, 20 mM sodium acetate buffer, 1 mM EDTA, pH 4.5.

제조 메모

Prepared from tissue of individuals that have been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.

재구성

Following initial thaw, aliquot and freeze (-70°C).

기타 정보

Note: 1 mU = 1 milliunit.

법적 정보

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

안전성 정보

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 2
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable