20-133-M

PKC Lipid Activator

• 동의어(들): PKC activator, Protein kinase C activator
• UNSPSC 코드: 41116012
• eCl@ss: 32160405
• NACRES: NA.41

속성

• 형태: liquid
• Quality Level: 100
• 제조업체/상표: Upstate^®
• 기술: activity assay: suitable (kinase)
• NCBI 수납 번호: NM_002737.2
• UniProt 수납 번호: P17252
• 유전자 정보: human ... PRKCA(5578)

설명

일반 설명

Protein kinase C (PKC) belongs to a family of serine/ threonine kinases. It comprises a regulatory domain at the N-terminus and a catalytic domain at the C-terminus. The regions are divided into conserved regions (C1–C4) and regions that differ between isoforms (V1–V5). PKC has a common pseudosubstrate domain in the regulatory region.

애플리케이션

For use in kinase assays.

Research Category
All

생화학적/생리학적 작용

Protein kinase C (PKC) is activated by diacylglycerol (DAG) and acts as an intracellular receptor of tumor-promoting phorbol esters. It regulates several cell functions and signal transduction pathways through cell migration and polarity, differentiation, proliferation, and cell death. PKC is part of a large group of phospholipid-dependent enzymes, which catalyze the covalent transfer of phosphate from ATP to serine and threonine residues of proteins.

물리적 형태

20mM MOPS, pH 7.2, 25mM β-glycerolphosphate, 1mM sodium orthovanadate, 1mM dithiothreitol, 1mM CaCl2.

저장 및 안정성

1 year at -20°C

법적 정보

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 2
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable