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Merck
모든 사진(1)

Key Documents

14-246-M

Sigma-Aldrich

p38γ/SAPK3 Protein, active, 10 µg

Active, recombinant GST fusion protein corresponding to full length human p38γ/SAPK3, for use in Kinase Assays.

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About This Item

UNSPSC 코드:
12352202
eCl@ss:
32160405
NACRES:
NA.32

생물학적 소스

human

Quality Level

재조합

expressed in E. coli

분자량

Mw 69 kDa

제조업체/상표

Upstate®

기술

activity assay: suitable (kinase)

NCBI 수납 번호

UniProt 수납 번호

유전자 정보

human ... PEBP1(5037)

일반 설명

Product Source: expressed in E. coli
Recombinant GST fusion protein corresponding to full length human p38γ/SAPK3

생화학적/생리학적 작용

Protein Target: p38γ/SAPK3
Target Sub-Family: CMGC

품질

Routinely evaluated by phosphorylation of MBP in vitro

저장 및 안정성

6 months at -70°C

기타 정보

For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.

법적 정보

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

픽토그램

Exclamation mark

신호어

Warning

유해 및 위험 성명서

Hazard Classifications

Skin Sens. 1

Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 2

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


시험 성적서(COA)

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문서 라이브러리 방문

The hepatitis B virus HBx protein inhibits caspase 3 activity
Gottlob, K., et al
The Journal of Biological Chemistry, 273, 33347-33353 (1998)
A Cuenda et al.
The EMBO journal, 16(2), 295-305 (1997-01-15)
Stress-activated protein kinase-3 (SAPK3), a recently described MAP kinase family member with a wide-spread tissue distribution, was transfected into several mammalian cell lines and shown to be activated in response to cellular stresses, interleukin-1 (IL-1) and tumour necrosis factor (TNF)
S P Davies et al.
The Biochemical journal, 351(Pt 1), 95-105 (2000-09-22)
The specificities of 28 commercially available compounds reported to be relatively selective inhibitors of particular serine/threonine-specific protein kinases have been examined against a large panel of protein kinases. The compounds KT 5720, Rottlerin and quercetin were found to inhibit many
Y Fleming et al.
The Biochemical journal, 352 Pt 1, 145-154 (2000-11-04)
Stress-activated protein kinase 1 (SAPK1), also called c-Jun N-terminal kinase (JNK), becomes activated in vivo in response to pro-inflammatory cytokines or cellular stresses. Its full activation requires the phosphorylation of a threonine and a tyrosine residue in a Thr-Pro-Tyr motif

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