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Merck
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Key Documents

03-0146-00

Millipore

SMC® Amyloid Beta 42 High Sensitivity Kit

1 kit sufficient for 96 wells, input: serum, plasma, cerebrospinal fluid (CSF)

동의어(들):

Abeta 1-42 immunoassay kit, Abeta 42 Single Molecule Counting Kit, Abeta 42 immunoassay kit, Abeta 42 ultra-sensitive Immunoassay

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About This Item

UNSPSC 코드:
12161503
NACRES:
NA.84

Quality Level

사용

 kit sufficient for 96 wells

종 반응성

human, rat, mouse

제조업체/상표

SMC®

assay range

sensitivity: 0.98 pg/mL
(lower limit of quantification)

inter-assay cv: <20%
intra-assay cv: <15%
standard curve range: 0.24-250 pg/mL

기술

ELISA: suitable
single molecule counting: suitable

입력

serum
plasma
cerebrospinal fluid (CSF)

호환성

for use with SMCxPRO® and Erenna<TMSYMBOL></TMSYMBOL> (validated)

배송 상태

wet ice

저장 온도

2-8°C

일반 설명

The SMC® Amyloid β1-42 High Sensitivity Immunoassay Kit contains all reagents required to perform the assay. This assay takes advantage of a standard immunoassay workflow configured in a standard plate format.

Assay protocols are similar to existing sandwich ELISA methods with two key differences:
1) Elution buffer disrupts the sandwich, separating the labeled detection antibody for quantification.
2)The Erenna and SMCxPRO® immunoassay systems detect analytes using Single Molecule Counting (SMC®) technology.

특이성

The capture antibody recognizes the C-terminal end of Amyloid beta 1-42, conferring specificity for Aβ42. No significant cross-reactivity to Aβ38 and Aβ40 was observed.

법적 정보

SMC is a registered trademark of Singulex
SMCxPRO is a registered trademark of Merck KGaA, Darmstadt, Germany

면책조항

Our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

픽토그램

Skull and crossbonesHealth hazard

신호어

Danger

유해 및 위험 성명서

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Irrit. 2 - Repr. 1B - STOT RE 2 Inhalation

표적 기관

Respiratory Tract

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects


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문서 라이브러리 방문

Chia-Liang Tsai et al.
Journal of clinical medicine, 8(10) (2019-10-09)
Nondemented people with a family history of Alzheimer's disease (ADFH) and the ApoE-4 allele have been demonstrated to show a trend for a higher probability of cognitive decline and aberrant levels of cognitive-related biomarkers. However, the potential interactive effects on

관련 콘텐츠

Learn how to integrate multiplex and high sensitivity immunoassay technology to further neuroscience research with MILLIPLEX® multiplex and Single Molecule Counting (SMC®) high sensitivity immunoassay detection of Alzheimer’s disease (AD) biomarkers in human cerebrospinal fluid, plasma, and serum samples.

Discover how to expand neuroscience biomarker research with high sensitivity immunoassays, such as Single Molecule Counting (SMC®) assays. These assays give researchers the tools they need to detect low-abundant blood-based biomarkers and expand biomarker options in neuroscience research.

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