N-078

(S)-N-Nitrosoanatabine solution

1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant^®

• 동의어(들): NAT
• 실험식(Hill 표기법): C₁₀H₁₁N₃O
• CAS Number: 71267-22-6
• Molecular Weight: 189.21
• UNSPSC 코드: 41116107
• NACRES: NA.24

속성

• Grade: certified reference material
• Quality Level: 300
• 형태: liquid
• 특징: (Snap-N-Spike^®)
• 포장: ampule of 1 mL
• 제조업체/상표: Cerilliant^®
• 농도: 1.0 mg/mL in acetonitrile
• 기술: gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• 응용 분야: forensics and toxicology
• 형식: single component solution
• 저장 온도: −20°C
• InChI: 1S/C10H11N3O/c14-12-13-7-2-1-5-10(13)9-4-3-6-11-8-9/h1-4,6,8,10H,5,7H2/t10-/m0/s1
• InChI key: ZJOFAFWTOKDIFH-JTQLQIEISA-N

설명

일반 설명

N-Nitrosoanatabine or NAT is a potent carcinogen and biomarker of exposure to cigarette smoke. It′s found in a variety of tobacco products such as cigarettes, electronic cigarettes, nicotine gum and oral snuff. This certified Snap-N-Spike^® solution is suitable for use in LC-MS/MS or GC/MS methods for nicotine testing, environmental monitoring, or clinical and diagnostic testing of nicotine biomarkers.

애플리케이션

• (S)-N-Nitrosoanatabine solution in Cytochrome P450 Inhibition Studies: Utilizing (S)-N-Nitrosoanatabine solution, researchers have elucidated its role in the inhibition of the cytochrome P450 2A13 enzyme, critical for understanding nicotine metabolism pathways and developing strategies to mitigate tobacco-related cancers. This study highlights the solution′s utility in biochemical research and pharmacological studies, serving as a critical analytical standard for assessing the metabolic pathways of tobacco alkaloid derivatives (Liu et al., 2016).

법적 정보

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

안전성 정보

• 픽토그램: GHS02,GHS07
• 신호어: Danger
• 유해 및 위험 성명서: H225,H302 + H312 + H332,H319
• 예방조치 성명서: P210 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P312 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 2
• Flash Point (°F): 35.6 °F - closed cup
• Flash Point (°C): 2.0 °C - closed cup