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Key Documents

840514P

Avanti

16:0-18:1 Phosphatidylethanol

Avanti Polar Lipids 840514P, powder

동의어(들):

1-palmitoyl-2-oleoyl-sn-glycero-3-phosphoethanol (sodium salt)

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About This Item

실험식(Hill 표기법):
C39H74NaO8P
CAS Number:
Molecular Weight:
724.96
UNSPSC 코드:
12352211
NACRES:
NA.25

분석

>99% (TLC)

형태

powder

포장

pkg of 2 × 100 mg (840514P-200mg)
pkg of 1 × 25 mg (840514P-25mg)

제조업체/상표

Avanti Polar Lipids 840514P

배송 상태

dry ice

저장 온도

−20°C

SMILES string

[H][C@@](COP([O-])(OCC)=O)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O.[Na+]

일반 설명

Phosphatidylethanol (PEth) is a phospholipid, that is generated in the presence of ethanol in cell membranes. PEths like PEth 16:0/18:1, PEth 18:1/18:1, and PEth 16:0/16:0 possesses a common phosphoethanol head. Two fatty acid chains of variable length and degree of saturation are bound to this head group.
Phosphatidylethanol (PEth) represents a group of glycerophospholipid homologues generated by substitution of ethanol for the lipid headgroup by the phospholipase D enzyme. Since the formation of PEth is specifically dependent on ethanol, the diagnostic specificity of PEth as an alcohol biomarker is theoretically 100%.

애플리케이션

16:0-18:1 Phosphatidylethanol may be used in surface planar bilayers (SPBs) formation.

생화학적/생리학적 작용

Phosphatidylethanols (PEths) serves as crucial biomarkers of alcohol consumption.

포장

5 mL Clear Glass Sealed Ampule (840514P-200mg)
5 mL Clear Glass Sealed Ampule (840514P-25mg)

법적 정보

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class Code

11 - Combustible Solids


시험 성적서(COA)

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문서 라이브러리 방문

Surface planar bilayers of phospholipids used in protein membrane reconstitution: an atomic force microscopy study
Domenech O, et al.
Colloids and Surfaces. B, Biointerfaces, 47(1), 102-106 (2006)
Anders Isaksson et al.
Drug testing and analysis, 3(4), 195-200 (2011-03-26)
Phosphatidylethanol (PEth) represents a group of glycerophospholipid homologues where ethanol by phospholipase D has been bound at the position that normally contains an amino-alcohol. Since the formation of PEth is specifically dependent on ethanol, the diagnostic specificity of PEth as
Alexandra Schröck et al.
Bioanalysis, 6(17), 2285-2294 (2014-11-11)
For early diagnosis and therapy of alcohol-related disorders, alcohol biomarkers are highly valuable. Concerning specificity, indirect markers can be influenced by nonethanol-related factors, whereas direct markers are only formed after ethanol consumption. Sensitivity of the direct markers depends on cut-offs
David Wensbo Posaric et al.
Analytical and bioanalytical chemistry, 406(19), 4735-4744 (2014-05-29)
Various phosphatidylethanol (PEth) derivatives, the corresponding reversed positional isomers (RPI-PEths), lyso-PEth-16:0, and penta-deuterium-labeled PEth analogs (d5-PEths), were synthesized by enzyme-independent synthetic routes. A general solvent system consisting of a mixture of acetone-d6 and methanol-d4 (97:3; v/v) was found to provide
The detection of 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphoethanol and ethyl glucuronide in human umbilical cord
Jones J, et al.
American Journal of Analytical Chemistry, 3(12), 800-800 (2012)

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