927708

2,2,11-trimethyl-4-oxo-3,8-dioxa-5,11-diazatetradecan-14-oic acid

≥95%

• 실험식(Hill 표기법): C₁₃H₂₆N₂O₅
• Molecular Weight: 290.36
• UNSPSC 코드: 12352106

속성

• Quality Level: 100
• 분석: ≥95%
• 형태: powder
• 반응 적합성: reagent type: linker
• 작용기: carboxylic acid; ester
• 저장 온도: 2-8°C

설명

애플리케이션

2,2,11-trimethyl-4-oxo-3,8-dioxa-5,11-diazatetradecan-14-oic acid is a heterobifunctional crosslinker useful for development of PROTAC degraders for targeted protein degradation or other bifunctional molecules in chemical biology. Incorporation of rigidity into the linker region may impact the 3D orientation of the molecules and thus ternary complex formation as well as optimization of drug-like properties. For linkers already conjugated to E3 ligase ligands, please visit our collection of Protein Degrader Building Blocks.

기타 정보

Technology Article: Degrader Building Blocks for Targeted Protein Degradation

Protein Degrader Building Blocks Portal

Crosslinkers for Bioconjugation

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable