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Merck
모든 사진(1)

문서

915858

Sigma-Aldrich

Poly(ethylene glycol)-block-poly(propylene glycol)-block-poly(ethylene glycol) diacrylate

average Mn ~5,800

동의어(들):

PEG-PPG-PEG, Pluronic P-123 diacrylate, Pluronic diacrylate

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About This Item

Linear Formula:
C3H3O[C2H4O]x[C3H6O]y[C2H4O]zC3H3O2
UNSPSC 코드:
51171641
NACRES:
NA.23

형태

solid

Quality Level

분자량

average Mn ~5,800

색상

off-white to yellow

저장 온도

−20°C

유사한 제품을 찾으십니까? 방문 제품 비교 안내

애플리케이션

Poloxamers are nonionic, triblock copolymers containg a central hydrophobic chain of poly(propylene glycol) (PPG) and two terminal hydrophilic chains of poly(ethylene glycol) (PEG). Due to their amphiphilic structure, poloxamer solutions feature temperature dependent self-assembling and thermo-gelling behavior. Concentrated aqueous solutions of poloxamers are liquid at low temperature and form a gel at higher temperature, in a reversible process. This characteristic has allowed for these materials to be used as drug carriers for most routes of administration including oral, topical, intranasal, ocular, and parenteral. Acrylate-modified derivatives are most commonly used as thermosensitive hydrogels for drug delivery and 3D bioprinting applications. After casting or printing, the material can be crosslinked to preserve the hydrogel structure.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


시험 성적서(COA)

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문서 라이브러리 방문

Smart hydrogels for 3D bioprinting
Shuai W, et al.
International Journal of Bioprinting, 1(1), 3-14 (2015)
Self-Assembly of Pluronic F127 Diacrylate in Ethylammonium Nitrate: Structure, Rheology, and Ionic Conductivity before and after Photo-Cross-Linking
Carlos R L, et al.
Macromolecules, 49(14), 5179-5189 (2016)
Photopolymerization of Pluronic F127 diacrylate: a colloid-templated polymerization
Manuela D B, et al.
Soft Materials, 7, 4928-4937 (2011)
J J Escobar-Chávez et al.
Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques, 9(3), 339-358 (2007-01-09)
It is, sometimes, desirable to maintain a constant plasma drug concentration within the therapeutically effective concentration range. The use of high viscosity hydromiscible vehicles such as hydrophilic gels, is one of various approaches for controlled drug delivery, and represents an
Christopher J Hansen et al.
Advanced materials (Deerfield Beach, Fla.), 25(1), 96-102 (2012-10-31)
Microvascular multinozzle arrays are designed and fabricated for high-throughput printing of functional materials. Ink-flow uniformity within these multigeneration, bifurcating microchannel arrays is characterized by computer modeling and microscopic particle image velocimetry (micro-PIV) measurements. Both single and dual multinozzle printheads are

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