모든 사진(1)
About This Item
Linear Formula:
(C6H5)3CSCH2CH(NH2)CO2H
CAS Number:
Molecular Weight:
363.47
Beilstein:
2339626
MDL number:
UNSPSC 코드:
12352209
eCl@ss:
32160406
PubChem Substance ID:
NACRES:
NA.22
product name
(+)-S-Trityl-L-cysteine, 97%
분석
97%
광학 활성
[α]25/D +115°, c = 0.8 in 0.04 M ethanolic HCl
반응 적합성
reaction type: solution phase peptide synthesis
mp
182-183 °C (dec.) (lit.)
응용 분야
peptide synthesis
SMILES string
N[C@@H](CSC(c1ccccc1)(c2ccccc2)c3ccccc3)C(O)=O
InChI
1S/C22H21NO2S/c23-20(21(24)25)16-26-22(17-10-4-1-5-11-17,18-12-6-2-7-13-18)19-14-8-3-9-15-19/h1-15,20H,16,23H2,(H,24,25)/t20-/m0/s1
InChI key
DLMYFMLKORXJPO-FQEVSTJZSA-N
유사한 제품을 찾으십니까? 방문 제품 비교 안내
애플리케이션
(+)-S-Trityl-L-cysteine, a non-natural, sulfur-containing amino acid is commonly used as a reagent in solution phase peptide synthesis (SPPS). It is also used as a metal-binding agent to synthesize substituted ferrocenoyl peptide conjugates using HBTU peptide coupling reagent for the cation-sensing applications solution via peptide-metal interactions.
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
이미 열람한 고객
Sébastien Brier et al.
Journal of molecular biology, 360(2), 360-376 (2006-06-20)
The mitotic kinesin Eg5 plays an essential role in establishing the bipolar spindle. Recently, several antimitotic inhibitors have been shown to share a common binding region on Eg5. Considering the importance of Eg5 as a potential drug target for cancer
James A D Good et al.
Journal of medicinal chemistry, 56(5), 1878-1893 (2013-02-12)
The mitotic kinesin Eg5 is critical for the assembly of the mitotic spindle and is a promising chemotherapy target. Previously, we identified S-trityl-L-cysteine as a selective inhibitor of Eg5 and developed triphenylbutanamine analogues with improved potency, favorable drug-like properties, but
Frank Kozielski et al.
Proteomics, 8(2), 289-300 (2008-01-11)
Mitotic kinesins represent potential drug targets for anticancer chemotherapy. Inhibitors of different chemical classes have been identified that target human Eg5, a kinesin responsible for the establishment of the bipolar spindle. One potent Eg5 inhibitor is S-trityl-L-cysteine (STLC), which arrests
Total synthesis of didmolamides A and B
You Shu-Li and Kelly JW
Tetrahedron Letters, 46(15), 2567-2570 (2005)
Daniel B Nichols et al.
European journal of medicinal chemistry, 49, 191-199 (2012-01-28)
Structure-based studies led to the identification of a constrained derivative of S-trityl-l-cysteine (STLC) scaffold as a candidate inhibitor of hepatitis C virus (HCV) NS5B polymerase. A panel of STLC derivatives were synthesized and investigated for their activity against HCV NS5B.
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