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Merck

VDR

vitamin D (1,25- dihydroxyvitamin D3) receptor

동의어:
NR1I1
:
UniProtKB ID:
Clone ID:
  • Human(7421) Summary: This gene encodes the nuclear hormone receptor for vitamin D3. This receptor also functions as a receptor for the secondary bile acid lithocholic acid. The receptor belongs to the family of trans-acting transcriptional regulatory factors and shows sequence similarity to the steroid and thyroid hormone receptors. Downstream targets of this nuclear hormone receptor are principally involved in mineral metabolism though the receptor regulates a variety of other metabolic pathways, such as those involved in the immune response and cancer. Mutations in this gene are associated with type II vitamin D-resistant rickets. A single nucleotide polymorphism in the initiation codon results in an alternate translation start site three codons downstream. Alternative splicing results in multiple transcript variants encoding different proteins. [provided by RefSeq, Feb 2011]
  • Mouse(22337) vitamin D receptor
  • Rat(24873) vitamin D (1,25- dihydroxyvitamin D3) receptor
  • chicken(395988) vitamin D (1,25- dihydroxyvitamin D3) receptor
  • dog(486588) vitamin D (1,25- dihydroxyvitamin D3) receptor
  • Horse(100034072) vitamin D (1,25- dihydroxyvitamin D3) receptor
  • domestic cat(100316614) vitamin D (1,25- dihydroxyvitamin D3) receptor
  • cow(533656) vitamin D (1,25- dihydroxyvitamin D3) receptor
  • sheep(101107273) vitamin D (1,25- dihydroxyvitamin D3) receptor
  • sheep(100294603) vitamin D (1,25- dihydroxyvitamin D3) receptor
  • naked mole-rat(101710294) vitamin D (1,25- dihydroxyvitamin D3) receptor
  • domestic guinea pig(100734655) vitamin D (1,25- dihydroxyvitamin D3) receptor

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Small Molecule - Agonist

제품 번호
설명
Calcifediol, United States Pharmacopeia (USP) Reference Standard,
human
Ergocalciferol (Vitamin D2), Pharmaceutical Secondary Standard; Certified Reference Material,
human
Cholecalciferol (Vitamin D3), Pharmaceutical Secondary Standard; Certified Reference Material,
human
Vitamin D3 solution, 1 mg/mL in ethanol, ampule of 1 mL, certified reference material, Cerilliant®,
human
Doxercalciferol, ≥98% (HPLC), solubility: >10 mg/mL in DMSO,
human

Small Molecule - Antagonist

제품 번호
설명
1α,25-Dihydroxyvitamin D3, ≥99% (HPLC),
human
1α,25-Dihydroxyvitamin D3, ≥97.0% (HPLC),
human

Antibodies

제품 번호
설명
종별 반응성
응용분야
Anti-Vitamin D Receptor antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human
응용분야
ELISA
immunofluorescence

immunohistochemistry

western blot
Monoclonal Anti-VDR antibody produced in mouse, clone 2F4, purified immunoglobulin, buffered aqueous solution,
종별 반응성
human
응용분야
ELISA
immunohistochemistry
Anti-VDR antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
종별 반응성
human
응용분야
immunofluorescence
western blot
Anti-VDR antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
종별 반응성
human
응용분야
immunofluorescence
Anti-VDR antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
종별 반응성
human
응용분야
immunofluorescence

esiRNA

제품 번호
설명
MISSION® esiRNA, targeting human VDR,
human