콘텐츠로 건너뛰기
Merck

UMOD

uromodulin

동의어:
ADMCKD2, FJHN, HNFJ, HNFJ1, MCKD2, THGP, THP
종:
UniProtKB ID:
Clone ID:
  • Human(7369) Summary: The protein encoded by this gene is the most abundant protein in mammalian urine under physiological conditions. Its excretion in urine follows proteolytic cleavage of the ectodomain of its glycosyl phosphatidylinosital-anchored counterpart that is situated on the luminal cell surface of the loop of Henle. This protein may act as a constitutive inhibitor of calcium crystallization in renal fluids. Excretion of this protein in urine may provide defense against urinary tract infections caused by uropathogenic bacteria. Defects in this gene are associated with the renal disorders medullary cystic kidney disease-2 (MCKD2), glomerulocystic kidney disease with hyperuricemia and isosthenuria (GCKDHI), and familial juvenile hyperuricemic nephropathy (FJHN). Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2013]
  • Mouse(22242) uromodulin
  • Rat(25128) uromodulin
  • domestic cat(101084248) uromodulin
  • dog(403510) uromodulin
  • cow(281567) uromodulin
  • sheep(101119604) uromodulin
  • naked mole-rat(101709895) uromodulin
  • domestic guinea pig(100730507) uromodulin

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

ELISA

Product Number
설명
Human UMOD / Uromodulin ELISA Kit, ,
human

Antibodies

Product Number
설명
종별 반응성
응용분야
Anti-UMOD antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
종별 반응성
human
응용분야
immunohistochemistry
Anti-UMOD antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
종별 반응성
human
응용분야
immunohistochemistry
Anti-Uromodulin/THP, ,
종별 반응성
human
응용분야
immunohistochemistry
western blot

Proteins

Product Number
설명
Tamm-Horsfall Glycoprotein, ,
human

esiRNA

Product Number
설명
MISSION® esiRNA, targeting human UMOD,
human