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Merck

STAT6

signal transducer and activator of transcription 6, interleukin-4 induced

동의어:
D12S1644, IL-4-STAT, STAT6B, STAT6C
:
UniProtKB ID:
Clone ID:
  • Human(6778) Summary: The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010]
  • Mouse(20852) signal transducer and activator of transcription 6
  • Rat(362896) signal transducer and activator of transcription 6, interleukin-4 induced
  • Zebrafish(337413) signal transducer and activator of transcription 6, interleukin-4 induced
  • Horse(100050053) signal transducer and activator of transcription 6, interleukin-4 induced
  • domestic cat(101089873) signal transducer and activator of transcription 6, interleukin-4 induced
  • dog(100142679) signal transducer and activator of transcription 6, interleukin-4 induced
  • chicken(100859196) signal transducer and activator of transcription 6, interleukin-4 induced
  • cow(353105) signal transducer and activator of transcription 6, interleukin-4 induced
  • sheep(101102134) signal transducer and activator of transcription 6, interleukin-4 induced
  • naked mole-rat(101725744) signal transducer and activator of transcription 6, interleukin-4 induced
  • Domestic Rabbit(100344264) signal transducer and activator of transcription 6, interleukin-4 induced
  • domestic guinea pig(100726686) signal transducer and activator of transcription 6, interleukin-4 induced

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ELISA

제품 번호
설명
Phosphotyrosine STAT6 / Signal Transducer and Activator of Transcription 6 ELISA Kit, ,
human
Cell-Based phospho-STAT ELISA Samper Kit for detecting phospho-STAT1 (pTyr701), phospho-STAT3 (pTyr705), and phospho-STAT5 (pTyr694) in cultured cell lines, 192 assays,
mouse, rat, human

Antibodies

제품 번호
설명
종별 반응성
응용분야
Anti-STAT6 antibody produced in rabbit, affinity isolated antibody, buffered aqueous glycerol solution,
종별 반응성
human
응용분야
immunofluorescence
immunohistochemistry

western blot
Anti-STAT6 (Ab-641) antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human
응용분야
immunohistochemistry
western blot
Anti-phospho-STAT6 (pTyr641) antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human
응용분야
immunohistochemistry
western blot
Anti-phospho-STAT6 (Tyr641) Antibody, clone 16E12, clone 16E12, Upstate®, from mouse,
종별 반응성
human, mouse, rat
응용분야
western blot
Anti-STAT6 Antibody, clone 4G7J8, Rabbit Monoclonal, ,
종별 반응성
mouse
응용분야
immunofluorescence
immunoprecipitation (IP)

western blot

Proteins

제품 번호
설명
STAT6, GST tagged human, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
human

esiRNA

제품 번호
설명
MISSION® esiRNA, targeting human STAT6,
human
MISSION® esiRNA, targeting mouse Stat6,
mouse