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Merck

STAT5B

signal transducer and activator of transcription 5B

동의어:
STAT5
:
UniProtKB ID:
Clone ID:
  • Human(6777) Summary: The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth hormones. It has been shown to be involved in diverse biological processes, such as TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression. This gene was found to fuse to retinoic acid receptor-alpha (RARA) gene in a small subset of acute promyelocytic leukemias (APLL). The dysregulation of the signaling pathways mediated by this protein may be the cause of the APLL. [provided by RefSeq, Jul 2008]
  • Mouse(20851) signal transducer and activator of transcription 5B
  • Rat(25126) signal transducer and activator of transcription 5B
  • domestic guinea pig(100716532) signal transducer and activator of transcription 5B
  • naked mole-rat(101722721) signal transducer and activator of transcription 5B
  • cow(282376) signal transducer and activator of transcription 5B
  • sheep(101122961) signal transducer and activator of transcription 5B
  • chicken(395556) signal transducer and activator of transcription 5B
  • domestic cat(101090663) signal transducer and activator of transcription 5B
  • dog(490969) signal transducer and activator of transcription 5B

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ELISA

제품 번호
설명
Cell-Based ELISA for detecting phospho-STAT5 (pTyr694) in cultured cell lines, 96 assays,
human

Antibodies

제품 번호
설명
종별 반응성
응용분야
Anti-STAT5B (ab2) antibody produced in rabbit, affinity isolated antibody,
종별 반응성
dog, horse, human, mouse, pig, rabbit, rat
응용분야
immunohistochemistry
western blot
Anti-STAT5B Antibody, Upstate®, from rabbit,
종별 반응성
human, mouse
응용분야
western blot
ANTI-STAT5B antibody produced in mouse, clone 2D1, purified immunoglobulin, buffered aqueous solution,
종별 반응성
human
응용분야
ELISA
immunofluorescence

immunohistochemistry

western blot
ANTI-STAT5B antibody produced in mouse, clone 1F5, purified immunoglobulin, buffered aqueous solution,
종별 반응성
human
응용분야
ELISA
western blot
Anti- STAT5B antibody produced in rabbit, ,
종별 반응성
human, mouse, rat
응용분야
immunohistochemistry
western blot

Proteins

제품 번호
설명
STAT5B Protein, recombinant,
human

esiRNA

제품 번호
설명
MISSION® esiRNA, targeting mouse Stat5b,
mouse
MISSION® esiRNA, targeting human STAT5B,
human