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Merck

RRM2B

ribonucleotide reductase M2 B (TP53 inducible)

동의어:
MTDPS8A, MTDPS8B, P53R2
:
UniProtKB ID:
Clone ID:
  • Human(50484) Summary: This gene encodes the small subunit of a p53-inducible ribonucleotide reductase. This heterotetrameric enzyme catalyzes the conversion of ribonucleoside diphosphates to deoxyribonucleoside diphosphates. The product of this reaction is necessary for DNA synthesis. Mutations in this gene have been associated with autosomal recessive mitochondrial DNA depletion syndrome, autosomal dominant progressive external ophthalmoplegia-5, and mitochondrial neurogastrointestinal encephalopathy. Alternatively spliced transcript variants have been described.[provided by RefSeq, Feb 2010]
  • Mouse(382985) ribonucleotide reductase M2 B (TP53 inducible)
  • Rat(299976) ribonucleotide reductase M2 B (TP53 inducible)
  • cow(528960) ribonucleotide reductase M2 B (TP53 inducible)
  • sheep(101123639) ribonucleotide reductase M2 B (TP53 inducible)
  • naked mole-rat(101718446) ribonucleotide reductase M2 B (TP53 inducible)
  • domestic guinea pig(100715485) ribonucleotide reductase M2 B (TP53 inducible)
  • Zebrafish(368909) ribonucleotide reductase M2 b
  • chicken(420253) ribonucleotide reductase M2 B (TP53 inducible)
  • Horse(100062030) ribonucleotide reductase M2 B (TP53 inducible)
  • domestic cat(101099777) ribonucleotide reductase M2 B (TP53 inducible)
  • dog(481988) ribonucleotide reductase M2 B (TP53 inducible)

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Antibodies

제품 번호
설명
종별 반응성
응용분야
Anti-P53R2 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
종별 반응성
human, mouse, rat
응용분야
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-RRM2B antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
종별 반응성
human
응용분야
immunofluorescence
immunohistochemistry
Monoclonal Anti-RRM2B antibody produced in mouse, clone 6C1, ascites fluid,
종별 반응성
human
응용분야
ELISA
western blot

Small Molecule - Inhibitor

제품 번호
설명
Hydroxycarbamide, British Pharmacopoeia (BP) Reference Standard,
human
Hydroxycarbamide, European Pharmacopoeia (EP) Reference Standard,
human
Hydroxyurea, United States Pharmacopeia (USP) Reference Standard,
human
Hydroxyurea, 98%, powder,
human
Gemcitabine hydrochloride, ≥98% (HPLC),
human

esiRNA

제품 번호
설명
MISSION® esiRNA, targeting human RRM2B,
human