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Merck

PRPH2

peripherin 2 (retinal degeneration, slow)

동의어:
AOFMD, AVMD, CACD2, DS, PRPH, RDS, RP7, TSPAN22, rd2
:
UniProtKB ID:
Clone ID:
  • Human(5961) Summary: The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein found in the outer segment of both rod and cone photoreceptor cells. It may function as an adhesion molecule involved in stabilization and compaction of outer segment disks or in the maintenance of the curvature of the rim. This protein is essential for disk morphogenesis. Defects in this gene are associated with both central and peripheral retinal degenerations. Some of the various phenotypically different disorders are autosomal dominant retinitis pigmentosa, progressive macular degeneration, macular dystrophy and retinitis pigmentosa digenic. [provided by RefSeq, Jul 2008]
  • Mouse(19133) peripherin 2
  • Rat(25534) peripherin 2
  • chicken(395899) peripherin 2 (retinal degeneration, slow)
  • dog(403972) peripherin 2 (retinal degeneration, slow)
  • domestic cat(727697) peripherin 2 (retinal degeneration, slow)
  • cow(280907) peripherin 2 (retinal degeneration, slow)
  • sheep(101109569) peripherin 2 (retinal degeneration, slow)
  • naked mole-rat(101702401) peripherin 2 (retinal degeneration, slow)
  • domestic guinea pig(100713395) peripherin 2 (retinal degeneration, slow)

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Antibodies

제품 번호
설명
종별 반응성
응용분야
Anti-PRPH2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
종별 반응성
human
응용분야
immunohistochemistry
western blot
Anti-Peripherin Antibody, serum, Chemicon®,
종별 반응성
bovine, human, mouse, pig, rat
응용분야
immunohistochemistry
western blot
Anti-Peripherin-2 Antibody, clone 6B10.1, clone 6B10.1, from mouse,
종별 반응성
human, mouse, rat
응용분야
immunohistochemistry
western blot

esiRNA

제품 번호
설명
MISSION® esiRNA, targeting human PRPH2,
human