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Merck

PRCP

prolylcarboxypeptidase (angiotensinase C)

동의어:
HUMPCP, PCP
종:
UniProtKB ID:
Clone ID:
  • Human(5547) Summary: The protein encoded by this gene is a lysosomal prolylcarboxypeptidase, which cleaves C-terminal amino acids linked to proline in peptides such as angiotension II, III and des-Arg9-bradykinin. The cleavage occurs at acidic pH, but the enzyme activity is retained with some substrates at neutral pH. This enzyme has been shown to be an activator of the cell matrix-associated prekallikrein. The importance of angiotension II, one of the substrates of this enzyme, in regulating blood pressure and electrolyte balance suggests that this gene may be related to essential hypertension. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]
  • Mouse(72461) prolylcarboxypeptidase (angiotensinase C)
  • Rat(293118) prolylcarboxypeptidase (angiotensinase C)
  • Zebrafish(436967) prolylcarboxypeptidase (angiotensinase C)
  • chicken(428096) prolylcarboxypeptidase (angiotensinase C)
  • Horse(100061830) prolylcarboxypeptidase (angiotensinase C)
  • domestic cat(101100665) prolylcarboxypeptidase (angiotensinase C)
  • dog(476788) prolylcarboxypeptidase (angiotensinase C)
  • domestic guinea pig(100734342) prolylcarboxypeptidase (angiotensinase C)
  • naked mole-rat(101719590) prolylcarboxypeptidase (angiotensinase C)
  • cow(534927) prolylcarboxypeptidase (angiotensinase C)
  • sheep(101107644) prolylcarboxypeptidase (angiotensinase C)

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ELISA

제품 번호
설명
Human PRCP ELISA, for serum, plasma and cell culture supernatants,
human

Antibodies

제품 번호
설명
종별 반응성
응용분야
Anti-PRCP antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
종별 반응성
human
응용분야
immunohistochemistry
western blot
Anti-PRCP antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
종별 반응성
human
응용분야
immunofluorescence
western blot

Proteins

제품 번호
설명
PrCP active human, recombinant, expressed in FreeStyle 293-F cells, ≥15% (SDS-PAGE),
human

esiRNA

제품 번호
설명
MISSION® esiRNA, targeting human PRCP,
human
MISSION® esiRNA, targeting mouse Prcp,
mouse