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Merck

POLR2A

polymerase (RNA) II (DNA directed) polypeptide A, 220kDa

동의어:
POLR2, POLRA, RPB1, RPBh1, RPO2, RPOL2, RpIILS, hRPB220, hsRPB1
:
UniProtKB ID:
Clone ID:
  • Human(5430) Summary: This gene encodes the largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a carboxy terminal domain composed of heptapeptide repeats that are essential for polymerase activity. These repeats contain serine and threonine residues that are phosphorylated in actively transcribing RNA polymerase. In addition, this subunit, in combination with several other polymerase subunits, forms the DNA binding domain of the polymerase, a groove in which the DNA template is transcribed into RNA. [provided by RefSeq, Jul 2008]
  • Mouse(20020) polymerase (RNA) II (DNA directed) polypeptide A
  • Rat(363633) polymerase (RNA) II (DNA directed) polypeptide A
  • domestic guinea pig(100734232) polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
  • naked mole-rat(101725588) polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
  • cow(282312) polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
  • sheep(100144762) polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
  • Zebrafish(553347) polymerase (RNA) II (DNA directed) polypeptide A
  • dog(479483) polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
  • domestic cat(101098500) polymerase (RNA) II (DNA directed) polypeptide A, 220kDa

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Antibodies

제품 번호
설명
종별 반응성
응용분야
Monoclonal Anti-POLR2A, (N-terminal) antibody produced in mouse, clone IF17, purified immunoglobulin, buffered aqueous solution,
종별 반응성
human
응용분야
ELISA
western blot
Anti-Phospho-POLR2A-S7 antibody produced in rabbit, ,
종별 반응성
human, mouse, rat
응용분야
western blot
Anti-Phospho-POLR2A-S5 antibody produced in rabbit, ,
종별 반응성
human
응용분야
western blot
Anti-Phospho-POLR2A-S5 antibody produced in rabbit, ,
종별 반응성
human, mouse, rat
응용분야
immunofluorescence
immunohistochemistry

western blot
Anti-POLR2A Antibody, clone 8H4A2, Rabbit Monoclonal, ,
종별 반응성
mouse
응용분야
western blot

Proteins

제품 번호
설명
RNA Polymerase II, C-terminal human, recombinant, expressed in E. coli, ≥85% (SDS-PAGE),
human
RNA Polymerase II, C-terminal domain, GST tagged human, recombinant, expressed in E. coli, ≥70% (SDS-PAGE),
human

esiRNA

제품 번호
설명
MISSION® esiRNA, targeting human POLR2A,
human
MISSION® esiRNA, targeting mouse Polr2a,
mouse