PML
promyelocytic leukemia
동의어:
MYL, PP8675, RNF71, TRIM19
종:
Human PML (5371), Mouse Pml (18854), Rat Pml (315713), chicken PML (415302), chicken PML (415304), Horse PML (100062744), domestic cat PML (101086975), dog PML (487641), cow PML (100138545), sheep PML (101111580) ...더
UniProtKB ID:
Clone ID:
- Human(5371) Summary: The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This phosphoprotein localizes to nuclear bodies where it functions as a transcription factor and tumor suppressor. Its expression is cell-cycle related and it regulates the p53 response to oncogenic signals. The gene is often involved in the translocation with the retinoic acid receptor alpha gene associated with acute promyelocytic leukemia (APL). Extensive alternative splicing of this gene results in several variations of the protein's central and C-terminal regions; all variants encode the same N-terminus. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
- Mouse(18854) promyelocytic leukemia
- Rat(315713) promyelocytic leukemia
- chicken(415302) promyelocytic leukemia
- chicken(415304) promyelocytic leukemia
- Horse(100062744) promyelocytic leukemia
- domestic cat(101086975) promyelocytic leukemia
- dog(487641) promyelocytic leukemia
- cow(100138545) promyelocytic leukemia
- sheep(101111580) promyelocytic leukemia
- naked mole-rat(101707749) promyelocytic leukemia
- domestic guinea pig(100720832) promyelocytic leukemia
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Antibodies
제품 번호
설명
종별 반응성
응용분야
Anti-PML antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human
응용분야
western blot
Anti-PML antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
종별 반응성
human
응용분야
immunohistochemistry
Anti-PML antibody, Mouse monoclonal, clone PML-97, purified from hybridoma cell culture,
종별 반응성
hamster, human, mouse
응용분야
ELISA
immunocytochemistry
immunoprecipitation (IP)
microarray
western blot
immunocytochemistry
immunoprecipitation (IP)
microarray
western blot
Rabbit anti-PML Antibody, Affinity Purified, Powered by Bethyl Laboratories, Inc.,
종별 반응성
human
응용분야
immunohistochemistry
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Anti-PML antibody produced in rabbit, ,
종별 반응성
human, mouse, rat
응용분야
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot