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Merck

PDK1

pyruvate dehydrogenase kinase, isozyme 1

동의어:
:
UniProtKB ID:
Clone ID:
  • Human(5163) Summary: Pyruvate dehydrogenase (PDH) is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals. The enzymatic activity is regulated by a phosphorylation/dephosphorylation cycle. Phosphorylation of PDH by a specific pyruvate dehydrogenase kinase (PDK) results in inactivation. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jun 2013]
  • Mouse(228026) pyruvate dehydrogenase kinase, isoenzyme 1
  • Rat(116551) pyruvate dehydrogenase kinase, isozyme 1
  • fruit fly(38017) Phosphoinositide-dependent kinase 1
  • Horse(100064091) pyruvate dehydrogenase kinase, isozyme 1
  • domestic cat(101092705) pyruvate dehydrogenase kinase, isozyme 1
  • dog(476828) pyruvate dehydrogenase kinase, isozyme 1
  • chicken(425972) pyruvate dehydrogenase kinase, isozyme 1
  • Zebrafish(555840) pyruvate dehydrogenase kinase, isozyme 1
  • Thale Cress(830330) 3'-phosphoinositide-dependent protein kinase 1
  • cow(528655) pyruvate dehydrogenase kinase, isozyme 1
  • sheep(101113205) pyruvate dehydrogenase kinase, isozyme 1
  • naked mole-rat(101705587) pyruvate dehydrogenase kinase, isozyme 1
  • Domestic Rabbit(100351323) pyruvate dehydrogenase kinase, isozyme 1
  • domestic guinea pig(100715937) pyruvate dehydrogenase kinase, isozyme 1

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Small Molecule - Activator

제품 번호
설명
Dichloroacetic acid, ReagentPlus®, ≥99%,
human, rat

Antibodies

제품 번호
설명
종별 반응성
응용분야
Anti-PDK1 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
종별 반응성
canine, human, mouse, rat
응용분야
ELISA
western blot
Anti-PDK1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
종별 반응성
human
응용분야
immunofluorescence
Anti-PDH kinase 1 Antibody, clone 1C7-H1 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
종별 반응성
human, mouse, rat
응용분야
affinity binding assay
flow cytometry

immunocytochemistry

immunohistochemistry

western blot
Anti-PDK1/PDHK1 Antibody, clone 5T6S8, Rabbit Monoclonal, ,
종별 반응성
human, rat
응용분야
immunohistochemistry
western blot
Monoclonal Anti-PDK1 antibody produced in mouse, clone 3E1, purified immunoglobulin, buffered aqueous solution,
종별 반응성
human
응용분야
ELISA

Small Molecule - Inhibitor

제품 번호
설명
Dichloroacetic acid, ReagentPlus®, ≥99%,
human, rat
Sodium dichloroacetate, 98%,
human

Proteins

제품 번호
설명
PDHK1, active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
human

esiRNA

제품 번호
설명
MISSION® esiRNA, targeting human PDK1,
human
MISSION® esiRNA, targeting mouse Pdk1,
mouse