PDHA1
pyruvate dehydrogenase (lipoamide) alpha 1
동의어:
PDHA, PDHCE1A, PHE1A
종:
Human PDHA1 (5160), Mouse Pdha1 (18597), Rat Pdha1 (29554), chicken PDHA1 (418610), domestic cat PDHA1 (101080765), dog PDHA1 (480858), cow PDHA1 (407109), sheep PDHA1 (101110118), domestic guinea pig Pdha1 (100735725), naked mole-rat Pdha1 (101716937)
UniProtKB ID:
Clone ID:
- Human(5160) Summary: The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle. The PDH complex is composed of multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). The E1 enzyme is a heterotetramer of two alpha and two beta subunits. This gene encodes the E1 alpha 1 subunit containing the E1 active site, and plays a key role in the function of the PDH complex. Mutations in this gene are associated with pyruvate dehydrogenase E1-alpha deficiency and X-linked Leigh syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2010]
- Mouse(18597) pyruvate dehydrogenase E1 alpha 1
- Rat(29554) pyruvate dehydrogenase (lipoamide) alpha 1
- chicken(418610) pyruvate dehydrogenase (lipoamide) alpha 1
- domestic cat(101080765) pyruvate dehydrogenase (lipoamide) alpha 1
- dog(480858) pyruvate dehydrogenase (lipoamide) alpha 1
- cow(407109) pyruvate dehydrogenase (lipoamide) alpha 1
- sheep(101110118) pyruvate dehydrogenase (lipoamide) alpha 1
- domestic guinea pig(100735725) pyruvate dehydrogenase (lipoamide) alpha 1
- naked mole-rat(101716937) pyruvate dehydrogenase (lipoamide) alpha 1
- Domestic Rabbit(100357349) pyruvate dehydrogenase (lipoamide) alpha 1
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
제품 번호
설명
종별 반응성
응용분야
Anti-PDHA1 Antibody, clone 1B13 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
종별 반응성
bovine, human, monkey, mouse, porcine, rat
응용분야
affinity binding assay
flow cytometry
immunocytochemistry
immunohistochemistry
western blot
flow cytometry
immunocytochemistry
immunohistochemistry
western blot
Anti-PDHA1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
종별 반응성
human
응용분야
immunohistochemistry
Anti-PDHA1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
종별 반응성
human
응용분야
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-phospho PDHE1-A type I (Ser300) Antibody, from rabbit, purified by affinity chromatography,
종별 반응성
xenopus, bovine, human, mouse, rat, zebrafish
응용분야
immunocytochemistry
western blot
western blot
ANTI-BDHA1 (CENTER) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
종별 반응성
human
응용분야
flow cytometry
western blot
western blot
Kits
제품 번호
설명
종
Pyruvate Dehydrogenase Activity Assay Kit, sufficient for 100 colorimetric tests,
종
rat, mouse, human