콘텐츠로 건너뛰기
Merck

OTX2

orthodenticle homeobox 2

동의어:
CPHD6, MCOPS5
종:
UniProtKB ID:
Clone ID:
  • Human(5015) Summary: This gene encodes a member of the bicoid subfamily of homeodomain-containing transcription factors. The encoded protein acts as a transcription factor and plays a role in brain, craniofacial, and sensory organ development. The encoded protein also influences the proliferation and differentiation of dopaminergic neuronal progenitor cells during mitosis. Mutations in this gene cause syndromic microphthalmia 5 (MCOPS5) and combined pituitary hormone deficiency 6 (CPHD6). This gene is also suspected of having an oncogenic role in medulloblastoma. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Pseudogenes of this gene are known to exist on chromosomes two and nine. [provided by RefSeq, Jul 2012]
  • Mouse(18424) orthodenticle homolog 2 (Drosophila)
  • Rat(305858) orthodenticle homeobox 2
  • Zebrafish(30501) orthodenticle homolog 2
  • cow(538953) orthodenticle homeobox 2
  • domestic cat(101094107) orthodenticle homeobox 2
  • chicken(395191) orthodenticle homeobox 2
  • dog(490708) orthodenticle homeobox 2
  • sheep(101114527) orthodenticle homeobox 2
  • domestic guinea pig(100729098) orthodenticle homeobox 2
  • naked mole-rat(101696878) orthodenticle homeobox 2
  • Domestic Rabbit(100009374) orthodenticle homeobox 2

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

제품 번호
설명
종별 반응성
응용분야
Monoclonal Anti-OTX2 antibody produced in mouse, clone 1H12C4B5, ascites fluid,
종별 반응성
human
응용분야
ELISA
flow cytometry

immunofluorescence

immunohistochemistry

western blot
Anti-OTX2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
종별 반응성
human
응용분야
immunohistochemistry
Anti-OTX2 antibody produced in rabbit, affinity isolated antibody,
종별 반응성
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat, sheep
응용분야
immunohistochemistry
western blot
Anti-OTX2 Antibody, clone 6I3J0, Rabbit Monoclonal, ,
종별 반응성
human, rat
응용분야
western blot
Anti-OTX2 Antibody, clone 1O4 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
종별 반응성
xenopus, bovine, horse, human, monkey, porcine, rat
응용분야
affinity binding assay
immunocytochemistry

immunohistochemistry

western blot

esiRNA

제품 번호
설명
MISSION® esiRNA, targeting human OTX2,
human
MISSION® esiRNA, targeting mouse Otx2,
mouse