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Merck

OPN4

opsin 4

동의어:
MOP
:
UniProtKB ID:
Clone ID:
  • Human(94233) Summary: Opsins are members of the guanine nucleotide-binding protein (G protein)-coupled receptor superfamily. This gene encodes a photoreceptive opsin protein that is expressed within the ganglion and amacrine cell layers of the retina. In mouse, retinal ganglion cell axons expressing this gene projected to the suprachiasmatic nucleus and other brain nuclei involved in circadian photoentrainment. In mouse, this protein is coupled to a transient receptor potential (TRP) ion channel through a G protein signaling pathway and produces a physiologic light response via membrane depolarization and increased intracellular calcium. The protein functions as a sensory photopigment and may also have photoisomerase activity. Experiments with knockout mice indicate that this gene attenuates, but does not abolish, photoentrainment. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
  • Mouse(30044) opsin 4 (melanopsin)
  • Rat(192223) opsin 4
  • naked mole-rat(101702306) opsin 4
  • domestic guinea pig(100724179) opsin 4
  • sheep(101111250) opsin 4
  • chicken(423609) opsin 4
  • dog(611027) opsin 4
  • domestic cat(493921) opsin 4
  • cow(515152) opsin 4

Custom & Knockdown Gene Products

  • siRNA

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Antibodies

제품 번호
설명
종별 반응성
응용분야
Anti-OPN4 antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human
응용분야
ELISA
western blot

esiRNA

제품 번호
설명
MISSION® esiRNA, targeting human OPN4,
human
MISSION® esiRNA, targeting mouse Opn4,
mouse