์ฝ˜ํ…์ธ ๋กœ ๊ฑด๋„ˆ๋›ฐ๊ธฐ
Merck

MYLK

myosin light chain kinase

๋™์˜์–ด:
AAT7, KRP, MLCK, MLCK1, MLCK108, MLCK210, MSTP083, MYLK1, smMLCK
์ข…:
Human MYLK (4638), Mouse Mylk (107589), Rat Mylk (288057), chicken MYLK (396445), dog MYLK (488012), Horse MYLK (100070482), cow MYLK (338037), naked mole-rat Mylk (101704236), Domestic Rabbit MYLK (100009143), domestic guinea pig Mylk (100714177)
UniProtKB ID:
Q15746, O95796, O95797, O95798, O95799, Q14844, Q16794, Q3ZCP9
Clone ID:
  • Human(4638) Summary: This gene, a muscle member of the immunoglobulin gene superfamily, encodes myosin light chain kinase which is a calcium/calmodulin dependent enzyme. This kinase phosphorylates myosin regulatory light chains to facilitate myosin interaction with actin filaments to produce contractile activity. This gene encodes both smooth muscle and nonmuscle isoforms. In addition, using a separate promoter in an intron in the 3' region, it encodes telokin, a small protein identical in sequence to the C-terminus of myosin light chain kinase, that is independently expressed in smooth muscle and functions to stabilize unphosphorylated myosin filaments. A pseudogene is located on the p arm of chromosome 3. Four transcript variants that produce four isoforms of the calcium/calmodulin dependent enzyme have been identified as well as two transcripts that produce two isoforms of telokin. Additional variants have been identified but lack full length transcripts. [provided by RefSeq, Jul 2008]
  • Mouse(107589) myosin, light polypeptide kinase
  • Rat(288057) myosin light chain kinase
  • chicken(396445) myosin light chain kinase
  • dog(488012) myosin light chain kinase
  • Horse(100070482) myosin light chain kinase
  • cow(338037) myosin light chain kinase
  • naked mole-rat(101704236) myosin light chain kinase
  • Domestic Rabbit(100009143) myosin light chain kinase
  • domestic guinea pig(100714177) myosin light chain kinase
  • sheep(443334) myosin light chain kinase

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Antibodies

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M7905
Monoclonal Anti-Myosin Light Chain Kinase antibody produced in mouse, clone K36, ascites fluid,
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avian, mammals
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immunoprecipitation (IP)
microarray
western blot
SAB1410811
Anti-MYLK antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
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human
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proximity ligation assay
western blot
HPA048055
Anti-MYLK antibody produced in rabbit, Prestige Antibodiesยฎ Powered by Atlas Antibodies, affinity isolated antibody,
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human
์‘์šฉ๋ถ„์•ผ
immunofluorescence
HPA031677
Anti-MYLK antibody produced in rabbit, Prestige Antibodiesยฎ Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
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human
์‘์šฉ๋ถ„์•ผ
immunohistochemistry
western blot
SAB5702330
Anti-MYLK Antibody, clone 1J2U2, Rabbit Monoclonal, ,
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human, rat
์‘์šฉ๋ถ„์•ผ
western blot

Small Molecule - Inhibitor

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I2764
ML-7, powder,
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human

Proteins

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M9197
MLCK (1425-1776), active, GST tagged human, PRECISIOยฎ Kinase, recombinant, expressed in baculovirus infected Sf9 cells, โ‰ฅ70% (SDS-PAGE), buffered aqueous glycerol solution,
์ข…
human

esiRNA

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EHU222191
MISSIONยฎ esiRNA, targeting human MYLK (2),
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human
EHU158801
MISSIONยฎ esiRNA, targeting human MYLK (1),
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human
EMU061601
MISSIONยฎ esiRNA, targeting mouse Mylk,
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mouse